Results 91 to 100 of about 21,361 (224)

Characterization of Pilin A and Thioredoxin A Mutant Strains of Acinetobacter baumannii, From a Transposon Insertion Library, for Pili Production and Virulence‐Associated Properties

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Acinetobacter baumannii transposon insertion mutant strains ΔpilA and ΔtrxA display marked reductions of surface pili. The PilA (a major pilin protein) and TrxA (thioredoxin A) deficient bacteria also show attenuation in pathogenesis including the reduction of intestinal bacterial attachment, increased phagocytic uptake and decreased mortality from ...
Jadelynn Aki, Sara B. Papp, Bayley Polk, Sean Jeffreys, Megan P. Tompkins, Anwar A. Kalalah, Mark Eppinger, Guoquan Zhang, M. N. Guentzel, James P. Chambers, Bernard P. Arulanandam, Jieh‐Juen Yu   +11 more
wiley   +1 more source

Atg5-Deficient Mice Infected with Francisella tularensis LVS Demonstrate Increased Survival and Less Severe Pathology in Internal Organs

Microorganisms, 2020
Francisella tularensis is a highly virulent intracellular pathogen that proliferates within various cell types and can infect a multitude of animal species. Francisella escapes the phagosome rapidly after infection and reaches the host cell cytosol where
Ina Kelava, Mirna Mihelčić, Mateja Ožanič, Valentina Marečić, Maša Knežević, Marija Ćurlin, Sanja Štifter, Anders Sjöstedt, Marina Šantić   +8 more
doaj   +1 more source

CGUG: in silico proteome and genome parsing tool for the determination of "core" and unique genes in the analysis of genomes up to ca. 1.9 Mb [PDF]

, 2009
Background Viruses and small-genome bacteria (~2 megabases and smaller) comprise a considerable population in the biosphere and are of interest to many researchers.
Padmanabhan Mahadevan, John F King, Donald Seto   +2 more
core   +1 more source

Ecology ofFrancisella tularensis

Annual Review of Entomology, 2020
Tularemia is a Holarctic zoonosis caused by the gamma proteobacterium Francisella tularensis and is considered to be a vector-borne disease. In many regions, human risk is associated with the bites of flies, mosquitoes, or ticks. But the biology of the agent is such that risk may be fomite related, and large outbreaks can occur due to inhalation or ...
Sam R, Telford, Heidi K, Goethert
openaire   +3 more sources

Zoonotic Disease Transmission May Be Linked to Host Co‐Occurrence Network Topology

Annals of the New York Academy of Sciences, Volume 1554, Issue 1, Page 110-120, December 2025.
A global analysis of zoonotic host co‐occurrence networks identified 22 networks from five continents (A) and 87 hosts from 16 orders of mostly birds but also mammals (B) as having a high potential for disease transmission. ABSTRACT Most human pathogens are zoonotic, transmitted from vertebrate hosts to humans.
Patrick T. Stillson, Brent B. Crow, William R. Budnick, Sophia I. Passy   +3 more
wiley   +1 more source

PCR and sequencing based methods for detection and typing of pathogenic microorganisms [PDF]

, 2011
The potential use of bacteria and viruses as biological terror weapons makes certain highly pathogenic microorganisms a worldwide public health threat.
Wahab, Tara
core   +1 more source

The European Union One Health 2024 Zoonoses Report

EFSA Journal, Volume 23, Issue 12, December 2025.
Abstract This report by the European Food Safety Authority and the European Centre for Disease Prevention and Control presents the results of zoonoses monitoring and surveillance activities carried out in 2024 in 27 Member States (MSs), the United Kingdom (Northern Ireland) and eight non‐MSs, according to the Zoonoses Directive 2003/99/EC.
European Food Safety Authority (EFSA) | European Centre for Disease Prevention and Control (ECDC)
wiley   +1 more source

Identification of Francisella novicida mutants that fail to induce prostaglandin E2 synthesis by infected macrophages.

Frontiers in Microbiology, 2013
Francisella tularensis is the causative agent of tularemia. We have previously shown that infection with F. tularensis Live Vaccine Strain (LVS) induces macrophages to synthesize prostaglandin E2 (PGE2). Synthesis of PGE2 by F.
Matthew Dale Woolard, Lydia M Barrigan, Lydia M Barrigan, James R Fuller, Adam S Buntzman, Joshua eBryan, Colin eManoil, Tom eKawula, Jeffrey A Frelinger   +8 more
doaj   +1 more source

Twin RNA Polymerase–associated Proteins Control Virulence Gene Expression in Francisella tularensis [PDF]

, 2012
The MglA protein is the only known regulator of virulence gene expression in Francisella tularensis, yet it is unclear how it functions. F. tularensis also contains an MglA-like protein called SspA.
Balon, Emmy, Boyd, Dana H., Charity, James Carl, Costante-Hamm, Michelle M, Dove, Simon L., Rubin, Eric Joseph, Schneewind, Olaf   +6 more
core   +1 more source

Francisella tularensisin Rodents, China

Emerging Infectious Diseases, 2006
A total of 420 rodents in China were examined for Francisella tularensis by polymerase chain reaction. The infection rates were 4.76% in total, and 11.65%, 10.00%, 6.56%, 1.77%, and 0% in Jilin, Xinjiang, Heilongjiang, Inner Mongolia, and Zhejiang, respectively. Sequence analysis showed that all the detected agents belonged to F.
Fang Zhang, Wei Liu, May C. Chu, Jun He, Qing Duan, Xiao-Ming Wu, Pan-He Zhang, Qiu-Min Zhao, Hong Yang, Zhong-Tao Xin, Wu-Chun Cao   +10 more
openaire   +3 more sources