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Francisella tularensis, the causative agent of tularemia, is a HHS Tier 1 select agent. Tularemia is the most commonly reported human and animal infection caused by a bacterial select agent in the United States. Because of the rarity of disease, low clinical suspicion, and the organism's low infectious dose, F.
Stephen, Morse, Richard, Henkel
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Iron and Virulence in Francisella tularensis [PDF]
Francisella tularensis, the causative agent of tularemia, is a Gram-negative bacterium that infects a variety of cell types including macrophages, and propagates with great efficiency in the cytoplasm. Iron, essential for key enzymatic and redox reactions, is among the nutrients required to support this pathogenic lifestyle and the bacterium relies on ...
openaire +2 more sources
Splenic, Nonhairy, B‐Cell Lymphoma Presenting as Fever of Unknown Origin
Fever of unknown origin (FUO) is a common diagnostic dilemma faced by internists on a fairly regular basis. A wide variety of infectious, autoimmune, and neoplastic conditions can present with FUO. Splenic B‐cell lymphoma/leukemia with prominent nucleolus (SBLPN), formerly known as hairy cell leukemia‐variant, is a hematologic malignancy that often ...
Abdul Rehman +5 more
wiley +1 more source
Acid Resistance in Francisella tularensis [PDF]
AbstractFrancisella tularensis, the etiologic agent of tularemia, can survive under acidic conditions. Tularemia can be acquired by several routes, including by ingestion of contaminated food or water. While acid resistance is usually associated with a low oral infective dose (ID), the ID for gastrointestinal illness is quite high.
Adcock, Noreen J +2 more
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Purpose Tick‐borne encephalitis (TBE), a zoonotic disease caused by the tick‐borne encephalitis virus (TBEV), usually manifests with a biphasic course with neurological involvement during its second phase. Extraneurological manifestations are rare but clinically relevant.
Marco Seneghini +5 more
wiley +1 more source
Azithromycin effectiveness against intracellular infections of
Background Macrolide antibiotics are commonly administered for bacterial respiratory illnesses. Azithromycin (Az) is especially noted for extremely high intracellular concentrations achieved within macrophages which is far greater than the serum ...
Mann Barbara J +4 more
doaj +1 more source
Lethal Case of Bourbon Virus Leading to Shock and ECMO Utilization
We present a lethal case of Bourbon virus infection in a 63‐year‐old Caucasian, diabetic male who was previously in good health. The patient had spent time in the wooded areas of Bourbon County, Kansas, and removed three ticks from his body 5 days prior to presentation.
Allianna Mitchell +7 more
wiley +1 more source
Sequencing and functional analysis of a Francisella tularensis pathogenicity island
Francisella tularensis, a Gram-negative coccobacillus, is an extremely virulent intracellular pathogen. Infection of humans with this pathogen results in tularemia, a life-threatening disease. An approximately 35 kb region found in the F.
Zhang, Na.
core
Francisella Tularensis: Tularemia
Francisella tularensis is the causative agent of tularemia. This emerging zoonosis shows several clinical manifestations complicating its diagnosis.
Sjöstedt, A. +5 more
core +1 more source
Francisella tularensis, causative agent of tularemia, is a contagious zoonotic ailment. This study was aimed to molecularly detect F. tularensis in tortoise blood (n = 100) and ticks (n = 100) collected in the West Azerbaijan province, Iran suing a ...
Amir Tukmechi +3 more
doaj +1 more source

