Results 91 to 100 of about 16,794 (216)

Proteome analysis of secerned proteins of Francisella tularensis [PDF]

open access: yes, 2016
Title of dissertation thesis: Proteome analysis of secerned proteins of Francisella tularensis The facultative intracellular bacterium Francisella tularensis is the causal agent of the infectious disease called tularaemia.
Konečná, Klára
core  

Francisella tularensis Subspecies holarctica, Tasmania, Australia, 2011

open access: yes, 2012
We report a case of ulceroglandular tularemia that developed in a woman after she was bitten by a ringtail possum (Pseudocheirus peregrinus) in a forest in Tasmania, Australia. Francisella tularensis subspecies holarctica was identified.
Alistair McGregor   +7 more
core   +1 more source

Underexplored Ligand‐Binding Features of FabI From Staphylococcus aureus and Escherichia coli: A Comparative Pharmacophoric Modeling and Surface Mapping Approach

open access: yesChemMedChem, Volume 21, Issue 15, 14 August 2026.
Antimicrobial resistance highlights the urgent need for novel FabI inhibitors. Using an integrated computational approach combining ConPhar pharmacophore modeling, FTMap surface mapping, and PLIP interaction profiling across experimental structures and structures from MD simulations, we identified a conserved binding core (Y156/Y157, A95) and ...
Pedro Tenório T. F. Leite   +10 more
wiley   +1 more source

Tularemia (Francisella tularensis)

open access: yes
Tularemia (Francisella tularensis) reviews exposure routes, clinical recognition, infection-control precautions, supportive field care, indications for testing or antimicrobial consultation, public-health considerations, and evacuation for worsening or ...
Casey C. Sears
core   +1 more source

Evolution of subspecies of Francisella tularensis

open access: yes, 2005
Analysis of unidirectional genomic deletion events and single nucleotide variations suggested that the four subspecies of Francisella tularensis have evolved by vertical descent. The analysis indicated an evolutionary scenario where the highly virulent F.
Larsson, Pär,   +5 more
core   +1 more source

An AraC/XylS Family Transcriptional Regulator Modulates the Oxidative Stress Response of Francisella tularensis

open access: yes, 2021
Francisella tularensis is a Gram-negative bacterium that causes a fatal human disease known as tularemia. The Centers for Disease Control and Prevention have classified F. tularensis as a category A tier 1 select agent.
Huang, Weihua   +13 more
core   +1 more source

Point of Care Testing and Recombinase Polymerase Amplification

open access: yes
Journal of Clinical Laboratory Analysis, Volume 40, Issue 20, October 2026.
Manfred Weidmann, Ahmed Abd El Wahed
wiley   +1 more source

Structural Modifications of Nonsteroidal Anti‐Inflammatory Drugs (NSAIDs): New Horizons in Antimicrobial Drug Discovery

open access: yesArchiv der Pharmazie, Volume 359, Issue 8, August 2026.
This review provides a comprehensive analysis of the molecular modifications applied to NSAIDs to develop novel antimicrobial agents. By focusing on structural changes and their impact on biological activity, the study highlights innovative strategies to combat the global challenge of antimicrobial resistance.
Ebru Koçak Aslan   +2 more
wiley   +1 more source

Detection of Francisellaceae and the differentiation of main European F. tularensis ssp. holarctica strains (Clades) by new designed qPCR assays

open access: yesBMC Microbiology
Background The zoonotic and highly infectious pathogen Francisella tularensis is the etiological agent of tularemia. Tularemia in humans is mainly caused by F. tularensis subspecies tularensis and holarctica, but Francisella species like F.
Kristin Köppen   +7 more
doaj   +1 more source

Schematic evolutionary tree of Francisella tularensis and Francisella genetic near neighbor species.

open access: yes, 2014
Black bars indicate the important canSNP signatures specific to major genetic groups among Francisella species and within F. tularensis. The three recognized subspecies*, as well as divisions within the two major subspecies, tularensis and holarctica ...
Emily Kaufman (200541)   +8 more
core   +1 more source

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