Results 111 to 120 of about 3,193,008 (366)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Why healthy eating is not equally attainable for all: a participatory systems perspective on dietary behaviour of people living on a low income in the Netherlands, and recommendations for systemic change

Archives of Public Health
Background Living on a low income is associated with multiple interacting factors and mechanisms that contribute to less healthy diets. Yet research has rarely examined these systemic drivers in depth among people on low incomes, including the ...
Sanne K. Djojosoeparto, Nieke A. Sonneveld, Carlijn B. M. Kamphuis, Maartje P. Poelman   +3 more
doaj   +1 more source

[Miscellaneous publications of the Association for the Prevention of Consumption, 1910-1912]

, 1911
Letter to the members of the Association for the Prevention of Consumption, 16 May ...
Association for the Prevention of Consumption
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Habitual coffee consumption and blood pressure: An epidemiological perspective

, 2008
This paper summarizes the current epidemiological evidence on coffee consumption in relation to blood pressure (BP) and risk of hypertension. Data from crosssectional studies suggest an inverse linear or U-shaped association of habitual coffee use with ...
Johanna M Geleijnse, Geleijnse, J.M.
core  

Decision letter for "Reconstruction of evolutionary changes in fat and toxin consumption reveals associations with gene losses in mammals: a case study for the lipase inhibitor PNLIPRP1 and the xenobiotic receptor NR1I3"

, 2021

openalex   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Understanding how social policy impacts health: a realist synthesis

Critical Public Health
Recognition that health should be considered in all policies is growing, highlighting the need to understand how social policies impact health. Social assistance benefits interventions (SABPI) and debt policy interventions (DPI) are particularly relevant,
Eline van Bennekom, Jantien van Berkel, Hilje van der Horst, Milou Haggenburg-Mohammed, Emely de Vet   +4 more
doaj   +1 more source

Affluence and Unsustainable Consumption Levels: The Role of Consumer Credit

, 2020
Several pressures on planetary boundaries are directly linked to the production of goods and services driven by people’s ever-increasing spending of money to improve their material living standard beyond a comfortable life.
Ahlström, Richard, Gärling, Tommy, ThØgersen, John, Ahlström, Richard,, Gärling, Tommy,   +4 more
core   +1 more source