Results 51 to 60 of about 1,334,272 (290)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

“İdeal”in Sınırında Bir Mücadele: Beden Olumlama Hareketi Üzerine Bir Alımlama Analizi

Erciyes İletişim Dergisi, 2019
Beden maddi bir varoluş olması anlamında bireysel olduğu kadar kamusaldır. Dolayısıyla toplumsal pratiklerden, kültürel kodlardan, tarihsel dönüşümlerden, söylemlerden bağımsız değildir.
Ceren Başal Yıldız, Beste Erdem
doaj   +1 more source

New Zealand culture of intoxication: Local and global influences [PDF]

, 2010
This article shows that attitudes towards and behaviours involving the consumption of alcohol in New Zealand have long been problematic. It provides an historical account of social, economic and legislative factors which have influenced the development ...
Campbell, Maxine M., McEwan, Brett James, Swain, David   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

CREATING VALUE WITHIN CONSUMPTION CULTURE

Studies and Scientific Researches: Economics Edition, 2016
The issue of culture consumption is a particular concern within the modern marketing theory. Culture can be seen as representing a body of knowledge, beliefs, values, attitudes, symbols etc, developed in a certain period of time by a group of individuals,
Daniel Adrian Gârdan, Gheorghe Epuran, Iuliana Petronela Gârdan   +2 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

'The Greek Fall: Simulacral Thanatotourism in Europe' [PDF]

, 2012
The paper explores the socio-cultural dynamics of Greek demonstrations in 2011, suggesting that their function exceeds that of social movements as we know them.
Tzanelli, R
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Türkiye Cumhuriyeti Tarihinde Yılbaşı Reklamları: Tüketim Kültürü Bağlamında 100 Yıllık Bir İnceleme

İletişim Kuram ve Araştırma Dergisi
Tüketim alışkanlıklarının kültürel etkenler çerçevesinde şekillendiği ve tüketimin bir kültür nesnesi haline geldiği tüketim kültüründe, özel günler tüketimle özdeşleşmiş birer pazarlama stratejisi konumuna gelmiştir.
Deniz Sezgin, Ülkem Irmak Şimşek
doaj   +1 more source

The political life of things: Explorations on material culture and consumption in Evangelical groups in Buenos Aires, Argentina [PDF]

, 2017
The aim of the article is to explore the material culture of Neo-Pentecostals´ mega-churches in Buenos Aires City, Argentina. In order to do this, we will reconstruct three consumers’ profile and the way that political senses are put into play.
Algranti, Joaquin Maria
core