Results 61 to 70 of about 11,053,629 (293)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The Transcript OPEN Library Political Science Model: A Sustainable Way into Open Access for E-Books in the Humanities and Social Sciences

open access: yesPublications, 2019
The strategic goal of the project “National Contact Point Open Access OA2020-DE” is to create the conditions for a large-scale open-access transformation in accordance with the Alliance of German Science Organizations.
Alexandra Jobmann, Nina Schönfelder
doaj   +1 more source

On the Equivalence Problem for Toric Contact Structures on S^3-bundles over S^2$

open access: yes, 2012
We study the contact equivalence problem for toric contact structures on $S^3$-bundles over $S^2$. That is, given two toric contact structures, one can ask the question: when are they equivalent as contact structures while inequivalent as toric contact ...
Banyaga   +11 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Study of structural parameters of petroleum acids and analysis of their possible negative impact on the environment

open access: yesЮг России: экология, развитие
Study of the structural parameters of petroleum acids isolated from oil from the Priozernoye field and analysis of their possible negative impact on the environment.The object of the study is and naphthenic acids isolated from the oil of the Priozernoye ...
L. V. Ivanova   +3 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Visual and optical performance of silicone hydrogel contact lenses for moderate myopia

open access: yesJournal of Optometry, 2010
Purpose: To compare the short-term visual and optical performance of silicone hydrogel contact lenses for myopia ≥ −3.00D. Methods: This was a short-term, non-dispense, double-masked, randomized study investigating Night&Day (ND), PureVision (PV), O2 ...
Nancy Keir   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Methylisothiazolinone and Methylchloroisothiazolinone New Insights [PDF]

open access: yesEuropean Medical Journal Dermatology, 2013
Methylisothiazolinone (MI), along with Kathon™ CG (methylchloroisothiazolinone/MI), are widely used preservatives to prevent bacterial overgrowth in aqueous solutions of various types of cosmetic, household, and industrial products. Because of its high
Ana Rita Rodrigues-Barata   +1 more
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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