Results 81 to 90 of about 3,549,018 (318)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Secondary transfer effects of intergroup contact via social identity complexity.

open access: yes, 2014
Secondary transfer effects (STEs) of intergroup contact refer to the generalization of contact effects from a primary encountered outgroup to attitudes towards secondary outgroups (Pettigrew, 2009). Using two large, cross-sectional data sets from Germany
Hewstone, Miles   +4 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Effect of Altered OCT Image Quality on Deep Learning Boundary Segmentation

open access: yesIEEE Access, 2020
Deep learning methods provide a platform to segment boundaries within the retina and choroid in OCT images of the posterior eye, with the ultimate goal of having a robust model that works well across a wide range of different datasets.
Jason Kugelman   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Contact Symplectic Fibrations and Bundle Contact Structures

open access: yesMediterranean Journal of Mathematics, 2023
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Contact urticaria to giraffe hair [PDF]

open access: yes, 2005
Background: Immediate-type hypersensitivity to animal proteins is a common problem in people occupationally exposed to animals. Methods: A 19-year-old female working as a voluntary zookeeper in her off-time suffered from hives on her forearms following ...
Placzek, M.   +3 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Barriers, motivators and enablers for dispensing multifocal contact lenses in Mumbai, India

open access: yesJournal of Optometry, 2015
Purpose: To understand the potential barriers, motivators and enablers in dispensing multifocal contact lenses (MFCL). Method: Two focus group discussions were conducted to design questionnaires regarding the prescribing habits for multifocal contact ...
Nilesh Thite   +3 more
doaj   +1 more source

Contact Lenses

open access: yesOphthalmology, 1987
Ophthalmology 94 (1987) 1355-1359.
Department of Ophthalmology, J. Hillis Miller Health Center, University of Florida, GainesvilleDepartment of OphthalmologyJ. Hillis Miller Health CenterUniversity of FloridaGainesville ( host institution )   +1 more
openaire   +3 more sources

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