Results 71 to 80 of about 11,053,629 (293)

Technology-Enabled Learning and the Benefits and Challenges of Using the Community of Inquiry Theoretical Framework

open access: yesInternational Journal of E-learning and Distance Education, 2019
The Introduction to Technology-Enabled Learning (TEL)MOOC was intended to engage teachers worldwide who work in any level of education and are interested in technology-enabled learning and Open Educational Resources.
Martha Cleveland-Innes   +4 more
doaj  

Study on Migrants and Formation Mechanism of Polyglycolic Acid Oligomers in Three Distinct Application Scenarios

open access: yesZhipu Xuebao
Poly (glycolic acid) (PGA) is an environmentally friendly, biodegradable polymer commonly utilized in biomedical applications. Due to its high thermal deformation temperature, favorable mechanical properties, and effective gas barrier capabilities, PGA ...
Sheng-feng LIU   +7 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The enhanced heat source model and its verification of unsteady heat transfer simulation in laser quenching based on experiment

open access: yesCase Studies in Thermal Engineering
Laser hardening, also known as laser phase transformation hardening, is a critical surface modification technology. In current engineering practice, the design of process parameters primarily relies on simulation. However, variations in actual conditions
Yutong Guo   +4 more
doaj   +1 more source

On overtwisted contact surgeries

open access: yes, 2017
In this note, we obtain a new result concluding when contact (+1/n)-surgery is overtwisted. We give a counterexample to a conjecture by James Conway on overtwistedness of manifolds obtained by contact surgery. We list some problems related to the contact
Onaran, Sinem
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

BOOK REVIEWS: The Politics of Encounter: Urban Theory and Protest Under Planetary Urbanization; Elections to the European Parliament as a Challenge for Democracy; and Transformations in Central Europe Between 1989 and 2012: Geopolitical, Cultural, and Socioeconomic Shifts

open access: yesBaltic Journal of Law & Politics, 2013
This article contains three book reviews. The reviewed books are: The Politics of Encounter: Urban Theory and Protest under Planetary Urbanization (2013) by Andy Merrifield; Elections to the European Parliament as a Challenge for Democracy, European ...
Kerikmäe Tanel   +2 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

On Contact Anosov Flows

open access: yes, 2003
Exponential decay of correlations for $\Co^{(4)}$ Contact Anosov flows is established. This implies, in particular, exponential decay of correlations for all smooth geodesic flows in strictly negative ...
Carlangelo, Liverani
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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