Results 111 to 120 of about 2,202,475 (315)

The Inhibition Mechanism of Pancreatic Ductal Adenocarcinoma via LXR Receptors: A Multifaceted Approach Integrating Molecular Docking, Molecular Dynamics and Post-MD Inter-Molecular Contact Analysis. [PDF]

Asian Pac J Cancer Prev, 2023
Agar S, Akkurt B, Ulukaya E.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Lubricated contact analysis of a spur gear pair with dynamic loads [PDF]

In the present research study, a comprehensive spur gear lubrication analysis has been carried out to understand the gear contact behaviour under lubrication conditions.
Liu, Huaiju
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Contact drying of particulate pharmaceuticals: modelling and simulation [PDF]

, 2010
In order to give a concrete response to the need of predictive contact drying simulation tools in pharmaceutical industry, simulation programs for contact drying of pharmaceutical powders were developed in this thesis work.
Intelvi, Marco
core  

THIN-WALLED FOUR-POINT CONTACT BALL BEARING CONTACT FINITE ELEMENT ANALYSIS

Jixie qiangdu, 2018
Based on the ANSYS finite element software,the method of dividing the contact area of the four point contact ball bearing is proposed. Establish a uniform thin four point contact ball bearing 1/2 single rolling and ring and the bearing finite element ...
WU Li, YAO TingQiang, WANG LiHua, LIU XiaoBao   +3 more
doaj  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Analysis of Contact Wheel and Tool Interaction in Belt Grinding

Journal of Machine Engineering
The belt grinding process is gaining an increasing importance in the industrial sector. Due to its high flexibility regarding the range of workpiece materials and its adaptability to various, even geometrically complex workpiece shapes and designs, belt ...
Julian Wolfgang Henning, Eckart Uhlmann, Michael Walter   +2 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The Contact Lens Impact on Quality of Life (CLIQ) questionnaire: development and validation

, 2009
NoPURPOSE. To develop and validate a questionnaire for the measurement of the impact of contact lenses on quality of life (QoL): The Contact Lens Impact on Quality of Life (CLIQ) Questionnaire. METHODS. The questionnaire was developed and validated using
Garamendi, Estibaliz, Pesudovs, Konrad, Elliott, David   +2 more
core   +1 more source