Results 41 to 50 of about 2,081,131 (218)
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Advances in Materials Science and Engineering, 2020 A numerical solution for line contact elastohydrodynamic lubrication (EHL) occurring on the rough surface of heterogeneous materials with a group of particles is presented in this study. The film thickness disturbance caused by particles and roughness is
Keying Chen +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
An Approach to Multicriteria Optimization of the Three-Stage Planetary Gear Train
MachinesPlanetary gear trains offer numerous advantages over traditional gear systems, including high efficiency, the ability to handle large torque loads, and significant reductions in mass and size for the same torque capacity.
Jelena Stefanović-Marinović +4 more
doaj +1 more source
Jixie chuandong, 2023 Aiming at the tooth profile contact problem of internal meshing gear transmission pairs with double contact points, the generation method of tooth profiles of the internal meshing gear transmission pair with double contact points is present.
Liang Dong +4 more
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
ANALYTICAL AND NUMERICAL METHODS TO OBTAIN CONTACT PATTERN OF CONVEXO-CONCAVE NOVIKOV GEARING [PDF]
Scientific Journal of Silesian University of Technology. Series Transport, 2014 Article presents analytical and numerical methods to obtain contact pattern of convexo-concave Novikov gearing. Two TCA (tooth contact analysis) methods were given wchich are based on equations of differential geometry. Difference between both of methods
Tadeusz MARKOWSKI, Michał BATSCH
doaj
Frictional contact problem in building constructions analysis
Magazine of Civil Engineering, 2020 The article discusses the contact interaction of deformable building constructions or their parts. Such interaction is realized for example at: hydraulic structures; suspension pile foundations, girder, raft, sheet piling; friction bearings and kinematic
Aleksandr Popov, Alexander Lovtsov
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source