Results 41 to 50 of about 2,202,475 (315)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Current patch test results with the European baseline series and extensions to it from the 'European Surveillance System on Contact Allergy' network, 2007-2008 [PDF]

, 2012
BACKGROUND: The pattern of contact sensitization to the supposedly most important allergens assembled in the baseline series differs between countries, presumably at least partly because of exposure differences. Objectives.
Jolanki, Riitta, Sansom, J.E., Beliauskiene, Aiste, Ormerod, Ad, Simon, D, Ballmer Weber B, Statham, Bn, Fuchs, T, Schuttelaar, Marie-Louise, Uter, W, Chowdhury, M.M., Sansom JE, Elsner, P., Sánchez-Pérez, Javier, Czarnecka-Operacz, Magda, English, Js, Fortina, Anna Belloni, Uter, W., Ormerod AD, García-Gavín J, Elsner, Peter, Rantanen, Tapio, Cooper, Sue, Fernandez-Redondo, V., García Gavín, J, Spiewak R, Gawkrodger, David J., Uter, Wolfgang, Ayala, Fabio, Fuchs, Thomas, Zmudzinska M, Bircher A, Sánchez-Pérez J, Carlos Armario-Hita, Jose, Kiec-Swierczynska M, Coenraads PJ, Sansom, Je, Aberer W, Larese, F., Fortina AB, Chowdhury, Mahbub M U, Fernández-Redondo V, Ballmer-Weber, Barbara, Giménez Arnau A, Brasch, J, Chowdhury, Mm, Schnuch, Axel, Gawkrodger, Dj, Brasch J, Balato, A, Aberer, W., Fernandez Vozmediano JM, Johansen JD, Fernández-Redondo, Virginia, Coenraads, Pieter-Jan, Green, Cathy M., Horne, Hl, Cooper, S., Brasch, Jochen, Mahler, Vera, Pesonen, M., Pesonen, Maria, Fernandez-Vozmediano, J.M., LARESE FILON, FRANCESCA, Giménez Arnau, A, Jolanki, R., English JS, Fernandez-Vozmediano JM, Fernández Redondo, Virginia, Rustemeyer, T., Schuttelaar, Marie-Louise; id_orcid, García Gavín J, Rantanen T, Coenraads, P.J., Armario-Hita JC, Fernandez-Vozmediano, Jose M., Ayala F, Garcia-Gavin, J., Mahler, V, Armario Hita JC, Aberer, Werner, Wilkinson M, Coenraads, Pj, Silvestre, J.F., Schnuch A., Balato, Anna, Elsner P, Sánchez Pérez J, Schuttelaar, Ml, Ormerod, Anthony D, Statham BN, Armario-Hita, José Carlos, Bauer, Andrea, Giménez-Arnau, Ana, Stone, N., Fernandez-Vozmediano, José M, Armario-Hita, J.C., Spiewak, R., Mahler V, Ballmer-Weber, B., Balato A, Green CM, Chomiczewska, D., Silvestre, Juan Fco, Fernández Redondo V, Fernández Redondo, V, Peserico, A, Sansom, Jane E, Chowdhury, Mahbub M. U., Bircher, A., Larese F, Zmudzinska, Maria, Statham, Barry N, Horne, H.L., Beliauskiene A, Wilkinson, Mark, Frosch, P.J., Green, Cm, Ayala, F, Simon, Dagmar, Spiewak, R, Larese, Francesca, Cooper, S, Bauer A, Fernandez Vozmediano, Jm, King, C.M., Armario Hita, Jc, Cooper S, Krêcisz B, Stone, N, Frosch, Peter J., Kiec Swierczynska, M, Krêcisz, Beata, Sanchez-Perez, J., Kiec Swierczynska M, Sansom, Jane E., Frosch, Pj, Aberer, W, Beliauskiene, A, Fuchs, T., Pesonen, Sini Maria Aliina, King, Clodagh M, Statham, Barry N., Rustemeyer, T, Rantanen, T, Sánchez Pérez, J, Czarnecka Operacz M, Horne HL, Ballmer-Weber B, Fortina, Ab, Elsner, P, Pesonen M, Fortina, A.B., English, J.S., PESERICO STECCHINI NEGRI DE SALVI, ANDREA, Peserico A, Jolanki, R, Wilkinson, M, King, Clodagh M., Ormerod, A.D., Silvestre, Jf, Chomiczewska, Dorota, Rustemeyer, Thomas, Kiec-Swierczynska, Marta, Rantanen, T., Krecisz, B., Gimenez-Arnau, A., Peserico, Andrea, English, John S C, Frosch PJ, Jolanki R, Spiewak, Radoslaw, Brasch, J., Gawkrodger, D.J., Czarnecka-Operacz, M., Bircher, A, Simon D, Uter W, Rustemeyer T, Horne, Helen L, Chomiczewska, D, Johansen, J.D., Kiec-Swierczynska, M., English, J.S.C., Silvestre JF, Schuttelaar, M.L., García-Gavín, Juan, Ayala, F., Peserico, A., Mahler, V., Bircher, Andreas, Zmudzinska, M., Balato, A., Simon, D., Wilkinson, M., King CM, Zmudzinska, M, Pesonen, M, Johansen, Jeanne Duus, Giménez-Arnau A, Bauer, A., Chomiczewska D, Green, Cathy M, BELLONI, FORTINA ANNA, Chowdhury MM, Schuttelaar ML, Stone N, English, John S. C., Gawkrodger, David J, Czarnecka-Operacz M, Stone, Natalie, Frosch, Peter J, Ballmer Weber, B, Krêcisz, B, Statham, B.N., Johansen, Jd, Fuchs T, Horne, Helen L., King, Cm, Chowdhury, M.M.U., Beliauskiene, A., Gawkrodger DJ, Schnuch, A., Ormerod, Anthony D., Czarnecka Operacz, M, Green, C.M., Bauer, A   +226 more
core   +1 more source

Analysis of SF6 contact based on QPSO-SVR

Energy Reports, 2023
In the condition evaluation of the high-voltage SF6 circuit breaker, contact resistance and mass loss have a significant impact on the arc contact. To that end, this paper proposes a method based on quantum particle swarm optimization and support vector ...
Jianwei Bai, Peijun Cong, Hui Zhang, Shixun Sun, Bowen Zhang, Yong Wang, Liang Wang   +6 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Contact Pressure and Shear Stress Analysis on Conforming Contact Problem

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2008
Two methods to solve a conforming contact problem are proposed. First method is general and can be applicable to the contact case between elastic arbitrary shape bodies.
Haruo NAGATANI, Akitoshi IMOU
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Finite element based surface roughness study for ohmic contact of microswitches [PDF]

, 2012
Finite element method (FEM) is used to model ohmic contact in microswitches. A determinist approach is adopted, including atomic force microscope (AFM) scanning real contact surfaces and generating rough surfaces with three-dimensional mesh.
Colin, Stephane, Hong Liu, Dimitri Leray, Stéphane Colin, Liu, Hong, Patrick Pons, Leray, Dimitri, Liu, H., Pons, P., Broué, A., Adrien Broué, Broue, Adrien, Pons, Patrick   +12 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Evaluation of Proximal Contact Tightness and Contact Area of Posterior Composite Resin Restorations

Applied Sciences
The purpose of this study is to evaluate the influence of the matrix system on proximal contact tightness (PCT) of posterior composite resin restorations.
Cem Peskersoy, Mert Sener, Oguz Baris Gurses, Eda Erbil, Murat Turkun   +4 more
doaj   +1 more source

Computerized generation and simulation of meshing of a novel crown gear coupling avoiding edge contact

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2019
To avoid the occurrence of the hub tooth tip edge contact with the sleeve tooth root flank and the sleeve tooth tip edge contact with the hub tooth root flank, a novel crown gear coupling composed of a hub with profile crowning, longitude crowning, and ...
Yabin GUAN, Xiaohui YANG, Zongde FANG
doaj   +1 more source