Results 61 to 70 of about 2,081,131 (218)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Three-way contact analysis characterizes the higher order organization of the Tcra locus. [PDF]
Nucleic Acids Res, 2023 Dai R +6 more
europepmc +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Analysis on Threaded Connection Sealing Performance of Deepwater Test String
Shiyou jixie, 2016 Sealing performance of deepwater test string directly affects test process safety and test result reliability.In order to solve sealing problem of threaded connection for deepwater test strings,a sealing weakness analysis method is proposed for deepwater
Meng Wenbo +5 more
doaj
Contact analysis and strength calculations of involute spline couplings. [PDF]
Sci Rep, 2023 Li S.
europepmc +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
In Situ Contact Analysis of Polyetheretherketone under Elastohydrodynamic Lubrication. [PDF]
Polymers (Basel), 2022 Hofmann S, Maier E, Lohner T.
europepmc +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Research on the Wheel-rail Matching in High-speed Railway under Different Traction Conditions
机车电传动, 2018 In order to study the contact characteristics of the new rail profile and the high-speed EMUs wheel profiles, the profiles matching between LMA, S1002CN, XP55 wheel and 60D, 60N rail in the middle position had been proceeded.
WANG Xueping, ZHANG Jun, MA He
doaj
Analysis of a dynamic thermo-elastic-viscoplastic contact problem
Electronic Journal of Qualitative Theory of Differential Equations, 2013 We consider a dynamic frictionless contact problem for thermo-elastic-viscoplastic materials with damage and adhesion. The contact is modeled with normal compliance condition.
Abdelaziz Azeb Ahmed +1 more
doaj +1 more source