Three-way contact analysis characterizes the higher order organization of the Tcra locus. [PDF]
Nucleic Acids Res, 2023 Dai R +6 more
europepmc +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Contact analysis and strength calculations of involute spline couplings. [PDF]
Sci Rep, 2023 Li S.
europepmc +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Analysis on Threaded Connection Sealing Performance of Deepwater Test String
Shiyou jixie, 2016 Sealing performance of deepwater test string directly affects test process safety and test result reliability.In order to solve sealing problem of threaded connection for deepwater test strings,a sealing weakness analysis method is proposed for deepwater
Meng Wenbo +5 more
doaj
In Situ Contact Analysis of Polyetheretherketone under Elastohydrodynamic Lubrication. [PDF]
Polymers (Basel), 2022 Hofmann S, Maier E, Lohner T.
europepmc +1 more source
Refining intra-protein contact prediction by graph analysis
BMC Bioinformatics, 2007 Background Accurate prediction of intra-protein residue contacts from sequence information will allow the prediction of protein structures. Basic predictions of such specific contacts can be further refined by jointly analyzing predicted contacts, and by
Eyal Eran +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The Inhibition Mechanism of Pancreatic Ductal Adenocarcinoma via LXR Receptors: A Multifaceted Approach Integrating Molecular Docking, Molecular Dynamics and Post-MD Inter-Molecular Contact Analysis. [PDF]
Asian Pac J Cancer Prev, 2023 Agar S, Akkurt B, Ulukaya E.
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source