The Inhibition Mechanism of Pancreatic Ductal Adenocarcinoma via LXR Receptors: A Multifaceted Approach Integrating Molecular Docking, Molecular Dynamics and Post-MD Inter-Molecular Contact Analysis. [PDF]
Asian Pac J Cancer Prev, 2023 Agar S, Akkurt B, Ulukaya E.
europepmc +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
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THIN-WALLED FOUR-POINT CONTACT BALL BEARING CONTACT FINITE ELEMENT ANALYSIS
Jixie qiangdu, 2018 Based on the ANSYS finite element software,the method of dividing the contact area of the four point contact ball bearing is proposed. Establish a uniform thin four point contact ball bearing 1/2 single rolling and ring and the bearing finite element ...
WU Li +3 more
doaj
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
A sensitivity analysis for frictionless contact problems
Computer Assisted Methods in Engineering and Science, 2023 A sensitivity analysis method for elasto-plastic contact problems with large deformation is developed based on two contact constraint methods, i.e., the Lagrange multiplier and penalty methods.
Xian Chen +2 more
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Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Analysis of Contact Wheel and Tool Interaction in Belt Grinding
Journal of Machine EngineeringThe belt grinding process is gaining an increasing importance in the industrial sector. Due to its high flexibility regarding the range of workpiece materials and its adaptability to various, even geometrically complex workpiece shapes and designs, belt ...
Julian Wolfgang Henning +2 more
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Metal-Semiconductor Field-Effect Transistors Fabricated Using DVT Grown n-MoSe2 Crystals With Cu-Schottky Gates [PDF]
Журнал нано- та електронної фізики, 2011 Metal-semiconductor field-effect transistors (MESFETs) based on DVT grown MoSe2 crystals and Cu Schottky gate have been fabricated and studied.
C.K. Sumesh +3 more
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