Results 41 to 50 of about 4,420,572 (300)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Forced spreading over superhydrophobic and copper surfaces
Dynamic spreading over superhydrophobic and copper surfaces was studied experimentally under the condition of contact line movement with speed greater than 1 mm/sec.
Feoktistov Dmitry +2 more
doaj +1 more source
The impact of the Corona, dielectric barrier discharge, and low pressure radiofrequency air plasmas on the chemical composition and wettability of medical grade polyvinylchloride was investigated.
Edward Bormashenko +4 more
doaj +1 more source
Automatic measurement of contact angle in pore-space images
A new approach is presented to measure the in-situ contact angle ( θ ) between immiscible fluids, applied to segmented pore-scale X-ray images. We first identify and mesh the fluid/fluid and fluid/solid interfaces. A Gaussian smoothing is applied to this
A. AlRatrout +3 more
semanticscholar +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
We propose a comprehensive immersed boundary-based dynamic contact angle framework capable of handling arbitrary surfaces of mixed wettabilities in three dimensions.
J. Göhl, A. Mark, S. Sasic, F. Edelvik
semanticscholar +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Surface wetting and contact angle: basics and characterisation
Wettability is of pivotal importance in many areas of science and technology, ranging from the extractive industry to development of advanced functional materials and biomedicine problems.
G. V. Beketov, O. V. Shynkarenko
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source

