Results 91 to 100 of about 1,174,398 (306)
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
BuildingsLarge-span structures may experience progressive collapse involving complex member collisions, for which efficient and accurate simulation remains a challenging problem in engineering practice.
Qiang Xu +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Lubricated contact analysis of a spur gear pair with dynamic loads [PDF]
In the present research study, a comprehensive spur gear lubrication analysis has been carried out to understand the gear contact behaviour under lubrication conditions.
Liu, Huaiju
core
An explicit solution to a three-dimensional wedge problem considering two edges effect
Friction, 2019 The paper presents an explicit matrix algorithm to solve the problem of an elastic wedge with three loaded surfaces. The algorithm makes use of a recently published concept of transformation matrix, by which the original surface loads are converted to ...
L. Guo +4 more
doaj +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
The effects of surface defects on the fatigue of water and oil lubricated contacts [PDF]
, 2000 A study into effects of surface defects on the rolling contact fatigue of brass and rail steel has been undertaken on a twin-disc rolling-sliding test machine with both oil and water lubrication.
Gao, N., Dwyer-Joyce, R. S.
core +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Influence of Error Factors on Transmission Contact for Spiral Bevel Gears
Jixie chuandong, 2023 The full tooth flank contact characteristic of the line contact spiral bevel gear transmission is sensitive to errors. To obtain the influence of error factors on transmission contact for line contact spiral bevel gears, the contact simulation analysis ...
Wang Mingyang, Li Shuwen, Sun Yuehai
doaj