Results 81 to 90 of about 1,129,525 (262)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
CONTACT AND ROTATION ANALYSIS OF SINGLE ROLLER ENVELOPING FACE WORM DRIVE
Jixie qiangdu, 2021 Based on the meshing theory of single roller enveloping end face worm drive,the distribution of contact line and the length of contact line on the cylindrical surface of the drive pair,and the self-rotation angle of the roller,and the self-rotation angle
LIAO HongHui +3 more
doaj
Particle-Bubble Interactions: an Investigation of the Three-Phase Contact Line by Atomic Force Microscopy. [PDF]
Langmuir, 2023 Nicklas J, Ditscherlein L, Peuker UA.
europepmc +1 more source
Patterned deposition at moving contact lines [PDF]
Advances in Colloid and Interface Science, 2014 When a simple or complex liquid recedes from a smooth solid substrate it often leaves a homogeneous or structured deposit behind. In the case of a receding non-volatile pure liquid the deposit might be a liquid film or an arrangement of droplets depending on the receding speed of the meniscus and the wetting properties of the system.
openaire +3 more sources
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Jixie chuandong, 2014 The gear contact stress is very difficult to calculate and test owing to complexity of gear pairs contact condition by manufacturing error,assembly error,support conditions,deformation of loaded gear pairs,etc.The gear contact can be constituted of line ...
徐恺 +4 more
doaj
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Stretching breakup of a conical liquid bridge with a moving contact line. [PDF]
RSC Adv, 2023 Xu XY +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source