Results 61 to 70 of about 1,589,316 (316)

A Comparative Study of Joint Clearance Effects on Dynamic Behavior of Planar Multibody Mechanical Systems

open access: yesLatin American Journal of Solids and Structures
Clearance always exists in actual joint due to many uncertainties such as machining tolerance, assemblage and load deformation. The main purpose of this paper is to propose a computational and experimental study on the dynamic characteristics of a planar
Yu Chen   +3 more
doaj   +1 more source

Numerical Comparison of Contact Force Models in the Discrete Element Method

open access: yesAerospace, 2022
The discrete element method (DEM) is usually applied in analyzing the scientifical origin/evolution of the asteroids and the landing/sampling of the regolith. In order to manage the contact between the non-spherical granules, the Polygonal Contact Model (
Ziwen Li   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Research on Spiral Sand Conveyor Based on Discrete Finite Element Simulation Technology

open access: yesShiyou jixie, 2021
The spiral sand conveyor is an important component of the sand mixer, mainly used to convey proppant. To study the functional relationship between the structural parameters of the spiral sand conveyor of the sand mixer and the sand conveying volume, as ...
Pan Lingyong   +3 more
doaj  

A microscopical model for electric‐mechanical contact [PDF]

open access: yesPAMM, 2003
AbstractIn this paper a model to deal with electric‐mechanical contact problems in the framework of the FEM is presented. On the basis of some micro‐mechanical studies, a new approach is developed to define the non‐linear constitutive law that governs the normal force‐displacement behaviour and the electric resistance of the contacting surfaces.
BOSO D   +2 more
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Quasidifferential modelling of adhesive contact

open access: yesMathematical and Computer Modelling, 1998
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Experimental Methods for Model Parameters in the Discrete Element Method

open access: yesKONA Powder and Particle Journal
The Discrete Element Method (DEM) is a widely used numerical method for studying, analyzing, and optimizing particulate processes. Based on contact models, DEM can predict the interactions of particles and particles with wall surfaces.
Fabian Krull   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy