Results 81 to 90 of about 1,589,316 (316)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Tracking contact transitions during force-controlled compliant motion using an interacting multiple model estimator [PDF]

open access: yes, 2001
This work concerns both monitoring of contact transitions and estimation of the unknown first-order geometric parameters during force-controlled motions. The robotic system is required to move an object among a sequence of contact configurations with the
Mihaylova, L.S.   +5 more
core  

Secondary transfer effects of intergroup contact : Alternative accounts and underlying processes

open access: yes, 2010
Although intergroup contact is one of the most prominent interventions to reduce prejudice, the generalization of contact effects is still a contentious issue.
Nicole Tausch   +30 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

When and why does extended contact work? The role of high quality direct contact and group norms in the development of positive ethnic intergroup attitudes amongst children [PDF]

open access: yes, 2011
This research examines quasi-experimentally for the first time whether direct contact moderates the extended contact effect amongst children, and whether the extended contact effect is mediated by either in-group or out-group norms about cross-ethnic ...
Adam Rutland   +7 more
core   +1 more source

Markov Model M/M/m/K in Contact Center

open access: yesAdvances in Electrical and Electronic Engineering, 2012
Our paper deals with a contact center dimensioning. The main task of a contact center is to offer services to customers. The most simple and genuine way of communication with the contact center agent is by phone.
Erik Chromy, Jan Diezka, Matej Kavacky
doaj   +1 more source

Finite element study of displacement controlled fretting in cylinder contact with different axis crossing angles

open access: yesAdvances in Mechanical Engineering, 2022
There is inevitably an angular offset during contact of mechanical structures such as roller bearings or gears. Most of the previous contact models involve the contact between two parallel cylinders.
Tieneng Guo, Ruguo Ji, Yunfei Ma
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Simulation Model and Ultrasound Study for Engineering Interfaces [PDF]

open access: yes, 2012
Friction and wear are experienced both in terms of machine operation and finance. They impact, amongst other things, energy consumption and material loss, product manufacture and component maintenance.
Zhu, Juanjuan
core  

Home - About - Disclaimer - Privacy