Results 71 to 80 of about 2,874,746 (299)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Abnormal high-$Q$ modes of coupled stadium-shaped microcavities

open access: yes, 2014
It is well known that the strongly deformed microcavity with fully chaotic ray dynamics cannot support high-Q modes due to its fast chaotic diffusion to the critical line of refractive emission.
Choi, Muhan   +5 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

齿轮传动中的齿面接触斑点分析与质量控制

open access: yesJixie chuandong, 2009
The evaluation method of the gear tooth sueface contact pattern and the new and old definition of the tooth surface contact pattern are introduced and compared.The evaluation method of the gear tooth surface contact pattern is proposed.Forming reason for
罗太景
doaj  

Peculiar Pattern of Irritant Contact Dermatitis to Semecarpus anacardium

open access: yesJournal of Marine Medical Society
Semecarpus anacardium (Family: Anacardiaceae), is a frequently used medicinal plant in alternative medicine. There has been few case reports suggesting the role of marking nut extract in allergic contact dermatitis.
Gopalsing Rameshsing Rajput   +3 more
doaj   +1 more source

Tailoring surface interactions, contact angles, drop topologies and self-assembly using laser irradiation

open access: yes, 2012
UV laser irradiation (lambda = 193 nm), below and above damage thresholds, is used to both alter and pattern the surface properties of borosilicate slides to tune and control the contact angle of a water drop over the surface.
Canning, John   +4 more
core   +1 more source

Slow dynamics and rare-region effects in the contact process on weighted tree networks [PDF]

open access: yes, 2012
We show that generic, slow dynamics can occur in the contact process on complex networks with a tree-like structure and a superimposed weight pattern, in the absence of additional (non-topological) sources of quenched disorder.
A. Barrat   +12 more
core   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Survey on Road-Tyre Contact Patch Pattern and Wear Related Aspects

open access: yesJournal of Mechanical Engineering, 2017
Motor vehicle end-users approaches to tyre safety issues in automobiles translate to a number of tyre failure risk factors. This study basically assessed tread wear pattern of tyres in passenger cars used on Nigeria roads. The result obtained showed that
Azodo Adinife Patrick
doaj   +1 more source

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