Results 91 to 100 of about 746,127 (308)

基于NURBS曲面的渐开线齿轮接触斑点解析及仿真

open access: yesJixie chuandong, 2014
According to the involute gear dynamic performance prediction,the whole involute gear tooth surface with modification is constructed based on NURBS by measurement of tooth surface to get the tooth surface data,and its accuracy is verified.Combining with ...
汪中厚, 马金妮, 康晓洁, 李刚
doaj  

Contingency planning for a deliberate release of smallpox in Great Britain : the role of geographical scale and contact structure [PDF]

open access: yes, 2010
Background: In the event of a release of a pathogen such as smallpox, which is human-to-human transmissible and has high associated mortality, a key question is how best to deploy containment and control strategies.
Hall, Ian   +11 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Online Biped Walking Pattern Generation with Contact Consistency [PDF]

open access: yes, 2015
In this paper, a novel online biped walking gait pattern generating method with contact consistency is proposed. Generally, it’s desirable that there is no foot-ground slipping during biped walking.
Wang, Jian   +3 more
core   +3 more sources

Human emotion and StO2: Dataset, pattern, and recognition of basic emotions [PDF]

open access: yes
Emotions can be recognized through facial expressions, but this becomes challenging when facial expressions are deliberately manipulated. This study introduces tissue oxygen saturation (StO2), a non-contact measured physiological signal of hemoglobin ...
Liu, Xinyu   +5 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Fabrication of Hydrophilic Surface on Rigid Gas Permeable Contact Lenses to Enhance the Wettability Using Ultraviolet Laser System

open access: yesMicromachines, 2019
The widely used rigid gas permeable (RGP) contact lenses provide higher oxygen permeability and tear exchange rate than do soft contact lenses. However, their wettability warrants improvement to enhance the wearing comfort.
Hsin-Yi Tsai   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Optimization of the loaded contact pattern in hypoid gears by automatic topography modification [PDF]

open access: yes, 2008
Systematic optimization of the tooth contact pattern under load is an open problem in the design of spiral bevel and hypoid gears. In order to enhance its shape and position, gear engineers have been assisted by numerical tools based on trial-and-error ...
GUIGGIANI, MASSIMO   +7 more
core   +1 more source

Home - About - Disclaimer - Privacy