Results 111 to 120 of about 746,127 (308)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

In vivo articular contact pattern of a total wrist arthroplasty design. [PDF]

open access: yesJ Biomech, 2021
Akhbari B   +7 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Surface defect characterisation using non-contact ultrasound [PDF]

open access: yes
Electromagnetic acoustic transducers (EMATs) have been used as a non-contact ultrasound approach for detecting and characterising surface defects in aluminium bars and billet.
Rosli, M. H.
core  

Analytical and Experimental Tooth Contact Pattern of Large-Sized Spiral Bevel Gears in Cyclo-Palloid System [PDF]

open access: yes, 2009
The demand of large-sized spiral bevel gears has increased in recent years and hereafter the demand may increase more and more. The large-sized spiral bevel gears with equi-depth teeth are usually manufactured based on Klingelnberg cyclo-palloid system ...
Isamu Tsuji, Kazumasa Kawasaki
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Tensile Specimen Circular Grid Pattern and AI-Based Strain Calculation Method

open access: yesApplied Sciences
During tensile testing of materials, strain measurement is conducted using either contact or non-contact methods. Contact methods offer high accuracy and precision but are limited by the specimen’s thickness and dimensions, whereas non-contact methods ...
Sarang Yi, Daeil Hyun, Seokmoo Hong
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

An Investigation into the Influence of the Contact Pressure Distribution at the Friction Pair Interface on Disc Brake Squeal [PDF]

open access: yes
The main purpose of this thesis is to investigate the dynamic centre of pressure during a noisy brake application. A novel technique is employed to measure the centre of pressure and contact pressure distribution between the disc/pad interfaces during ...
Ashraf, Naveed
core  

Comparative analysis of numerical methods for the determination of contact pattern of spiral bevel gears [PDF]

open access: yes, 2018
Purpose This paper aims to present a comparison of numerical methods for determining the contact pattern of Gleason-type bevel gears. The mathematical model of tooth contact analysis and the finite element method were taken into consideration ...
Pawel Fudali   +3 more
core   +1 more source

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