Results 101 to 110 of about 746,127 (308)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

A phenomenological approach to the deposition pattern of evaporating droplets with contact line pinning [PDF]

, 2018
When an evaporating droplet of colloidal suspension dries on a solid surface with the contact line pinned, the solute particles are driven by the solvent flow toward the edge and form a ring-like deposition pattern. In this work, we take into account the
Wang, Haiqin, Yan, Dadong, Qian, Tiezheng   +2 more
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

齿面研磨边界的确定与研齿性能试验

Jixie chuandong, 2007
Based on the tooth contact simulation and the analysis of transmission errors and contact ratio on the lapping process,the lapping boundary of the tooth surface is determined:±0.25～0.3 face width and ±0.1～0.25 tooth height in the middle of tooth surface ...
魏冰阳, 毛玺, 杨宏斌, 方宗德
doaj  

Social contacts patterns relevant to the transmission of infectious diseases in Suzhou, China following the COVID-19 epidemic

Journal of Health, Population and Nutrition
Background The COVID-19 pandemic has profoundly affected human social contact patterns, but there is limited understanding regarding the post-pandemic social contact patterns.
Mengru Wang, Congju Wang, Guoping Gui, Feng Guo, Risheng zha, Hongpeng Sun   +5 more
doaj   +1 more source

Optimization of Rear Local Contacts on High Efficiency PERC Solar Cells Structures

International Journal of Photoenergy, 2013
A local contact formation process and integration scheme have been developed for the fabrication of rear passivated point contact solar cells. Conversion efficiency of 19.6% was achieved using  mm, pseudo square, p-type single crystalline silicon wafers.
Kapila Wijekoon, Fei Yan, Yi Zheng, Dapeng Wang, Hemant Mungekar, Lin Zhang, Hari Ponnekanti   +6 more
doaj   +1 more source

Contact pattern, current immune barrier, and pathogen virulence determines the optimal strategy of further vaccination. [PDF]

Infect Dis Model, 2023
Guo X, Liu Z, Yang S, Zhao Z, Guo Y, Abudurusuli G, Zhao S, Zeng G, Hu S, Luo K, Chen T.   +10 more
europepmc   +1 more source

International Conference on Pattern Recognition: Applications and Methods - 2013 [PDF]

, 2013
The International Conference on Pattern Recognition Applications and Methods would like to become a major point of contact between researchers, engineers and practitioners on the areas of Pattern Recognition, both from theoretical and application ...
DE MARSICO, Maria, Ana Fred
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

The effect of SU-8 patterned surfaces on the response of the quartz crystal microbalance [PDF]

, 2004
In this work we present data showing the effect of patterning layers of SU-8 photoresist on a quartz crystal microbalance (QCM) and subsequent chemical treatment to increase their hydrophobicity. Patterns with 5 mu m diameter pillars spaced every 10 mu m
Evans, Carl, Newton, Michael, Stanley, SM, Stanley, Simon, Newton, MI, Shirtcliffe, Neil, McHale, G, Shirtcliffe, NJ, McHale, Glen, Evans, CR   +9 more
core   +1 more source