Results 81 to 90 of about 746,127 (308)

Survey on Road-Tyre Contact Patch Pattern and Wear Related Aspects

open access: yesJournal of Mechanical Engineering, 2017
Motor vehicle end-users approaches to tyre safety issues in automobiles translate to a number of tyre failure risk factors. This study basically assessed tread wear pattern of tyres in passenger cars used on Nigeria roads. The result obtained showed that
Azodo Adinife Patrick
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Emergence of embryonic pattern through contact inhibition of locomotion [PDF]

open access: yes, 2012
The pioneering cell biologist Michael Abercrombie first described the process of contact inhibition of locomotion more than 50 years ago when migrating fibroblasts were observed to rapidly change direction and migrate away upon collision.
Dunn, Graham   +15 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Modification and Control Technology of Contact Zone of the Straight Bevel Gear

open access: yesJixie chuandong, 2020
The GB/T 11365-2019 provides that the tooth contact pattern of straight bevel gear is agreed by both supply and customer,and there is no direct relationship between tooth contact pattern and gear accuracy classification.
Li Yufan, Nan Boru, Gao Bin
doaj  

Tooth Contact Analysis and Adjustment Calculation of Real Tooth Surfaces of Hypoid Gears

open access: yesJixie chuandong, 2023
For the purpose of adjusting the calculation of the contact pattern of real hypoid gears, the double third-power spline surface is used for fitting tooth surfaces of pinions and gears accurately according to the measurement results of the gear surface ...
Han Kunpeng, Yang Jianjun
doaj  

Computerized Modeling and Loaded Tooth Contact Analysis of Hypoid Gears Manufactured by Face Hobbing Process

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2009
The face hobbing process has been widely applied in automotive industry. But so far few analytical tools have been developed. This makes it difficult for us to optimize gear design.
Takayuki NISHINO
doaj   +1 more source

New supercurrent pattern in quantum point contact with strained graphene nanoribbon

open access: yesNew Journal of Physics, 2020
We theoretically reveal the unusual features of the Josephson effect in a strained zigzag graphene nanoribbon with a small length relative to the superconducting coherence length and an arbitrary width.
Leyla Majidi, Reza Asgari
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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