Results 31 to 40 of about 608,104 (263)

Contact Problems in Porous Media

open access: yesComputational Methods in Applied Mathematics
Abstract The Biot problem of poroelasticity is extended by Signorini contact conditions. The resulting Biot contact problem is formulated and analyzed as a two field variational inequality problem of a perturbed saddle point structure. We present an a priori error analysis for a general as well as for an hp-FE discretization including ...
Lothar Banz, Fleurianne Bertrand
openaire   +3 more sources

A Population‐Based Study on Childhood Aplastic Anemia—Incidence, Outcomes, and Health‐Related Quality of Life

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala   +8 more
wiley   +1 more source

On Nitsche's Method for Elastic Contact Problems [PDF]

open access: yesSIAM Journal on Scientific Computing, 2020
We show quasi-optimality and a posteriori error estimates for the frictionless contact problem between two elastic bodies with a zero-gap function. The analysis is based on interpreting Nitsche's method as a stabilised finite element method for which the error estimates can be obtained with minimal regularity assumptions and without the saturation ...
Stenberg, Rolf   +3 more
openaire   +4 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Double pendulum contact problem

open access: yesApplied and Computational Mechanics, 2014
The work concerns contact problems focused on biomechanical systems modelled by a multibody approach. The example is modelling of impact between a body and an infrastructure. The paper firstly presents algorithm for minimum distance calculation.
Špička J., Hynčík L., Hajžman M.
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli   +5 more
wiley   +1 more source

3D CONTACT PROBLEM ON INTERACTION BETWEEN FLEXIBLE WEDGE AND TWO PUNCHES UNDER FRICTION

open access: yesВестник Донского государственного технического университета, 2018
The spatial contact problem for the flexible wedge is investigated in the quasi-static formulation when two identical elliptic rigid punches are symmetrically impressed into one face of the wedge under friction. The other wedge face is stress-free.
Dmitry Alexandrovich Pozharskiy   +1 more
doaj  

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao   +5 more
wiley   +1 more source

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