Results 41 to 50 of about 7,764,115 (299)

Contact Problems in Porous Media

open access: yesComputational Methods in Applied Mathematics
Abstract The Biot problem of poroelasticity is extended by Signorini contact conditions. The resulting Biot contact problem is formulated and analyzed as a two field variational inequality problem of a perturbed saddle point structure. We present an a priori error analysis for a general as well as for an hp-FE discretization including ...
Lothar Banz, Fleurianne Bertrand
openaire   +5 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

On Nitsche's Method for Elastic Contact Problems [PDF]

open access: yesSIAM Journal on Scientific Computing, 2020
We show quasi-optimality and a posteriori error estimates for the frictionless contact problem between two elastic bodies with a zero-gap function. The analysis is based on interpreting Nitsche's method as a stabilised finite element method for which the error estimates can be obtained with minimal regularity assumptions and without the saturation ...
Stenberg, Rolf   +3 more
openaire   +4 more sources

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Double pendulum contact problem

open access: yesApplied and Computational Mechanics, 2014
The work concerns contact problems focused on biomechanical systems modelled by a multibody approach. The example is modelling of impact between a body and an infrastructure. The paper firstly presents algorithm for minimum distance calculation.
Špička J., Hynčík L., Hajžman M.
doaj  

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

The adhesive contact of a flat punch on a hyperelastic substrate subject to a pull-out force or a bending moment

open access: yes, 2011
In the last decade; instrumented macro- and nano-indentation tests have become useful tools for probing mechanical properties of materials. In this context, little in-depth work has been done for soft bio-materials like biofilms, tissues, gels, cells ...
Zisis, T.   +8 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Ismaili Contact (Europe) Silver Jubilee [PDF]

open access: yes, 1982
Ismaili Contact (Europe) Silver Jubilee - Salegreh 1982https://ecommons.aku.edu/arch_research_publications_secondary-sources/1033/thumbnail ...
Ismaili Contact,
core   +1 more source

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