Results 31 to 40 of about 3,972,720 (284)
A positioning sensor for tonometric applications [PDF]
, 1992 In this paper we present a sensor, which is designed for application in a tonometer, an instrument for the measurement of intraocular pressure. The sensor measures diameter and position of a part of the eye globe that is flattened by the tonometer.
Bergveld, P., Besten, C. den
core +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Formulations of the deformable foundation contact problems
Journal of Civil Engineering and Management, 2002 Up to now in many works a construction on elastic foundation was modelled by the Winkler's hypothesis. In this paper the flexible plate-foundation system is investigated as an interaction of separate elastic bodies, which lie on the contact surface. Such
Stanislovas Kalanta +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
High Voltage, 2020 Dielectric response measurement is a widely used technique for characterising dielectric materials in terms of their capacitance and dielectric loss. However, the widely used approach with contact between samples and electrodes can in some cases limit ...
Jing Hao, Xiangdong Xu, Nathaniel Taylor
doaj +1 more source
Tykhonov well-posedness of fixed point problems in contact mechanics
Fixed Point Theory and Algorithms for Sciences and Engineering, 2022 We consider a fixed point problem S u = u $\mathcal {S}u=u$ where S : C ( R + ; X ) → C ( R + ; X ) ${\mathcal {S}:C(\mathbb{R}_{+};X)\to C(\mathbb{R}_{+};X)}$ is an almost history-dependent operator.
Mircea Sofonea
doaj +1 more source
Noether Theorem in Stochastic Optimal Control Problems via Contact Symmetries
Mathematics, 2021 We establish a generalization of the Noether theorem for stochastic optimal control problems. Exploiting the tools of jet bundles and contact geometry, we prove that from any (contact) symmetry of the Hamilton–Jacobi–Bellman equation associated with an ...
Francesco C. De Vecchi +3 more
doaj +1 more source
A phase-field method for modeling cracks with frictional contact
, 2019 We introduce a phase-field method for continuous modeling of cracks with frictional contacts. Compared with standard discrete methods for frictional contacts, the phase-field method has two attractive features: (1) it can represent arbitrary crack ...
Choo, Jinhyun, Fei, Fan
core +2 more sources