Results 41 to 50 of about 3,972,720 (284)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

NUMERICAL AND ANALYTICAL PROBLEMS OF FATIGUE STRENGTH IN ROLLING BEARINGS [PDF]

Scientific Journal of Silesian University of Technology. Series Transport, 2014
The aim of the work is to create an algorithm of fatigue life prediction for typical rolling bearings. The proposed approach makes use of various, well established hypothesis for multiaxial fatigue applied in engineering calculations. In the first part
Paweł ROMANOWICZ, Bogdan SZYBIŃSKI
doaj  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Solutions for contact problems applied to bevel gears [PDF]

E3S Web of Conferences
The article presents solutions to flat contact problems applied to straight-tooth bevel gears, considering both linear and nonlinear dependencies between elastic displacements of the teeth and the resulting stresses.
Savenkov Oleg, Voronenko Serhii, Sadovoy Oleksiy, Poltorak Anastasiya   +3 more
doaj   +1 more source

A new smooth contact element: 3D diffuse contact element [PDF]

International Journal for Simulation and Multidisciplinary Design Optimization, 2008
Many difficulties due to geometrical and material non-linearities arise when dealing with numerical simulation of contact problems. Within a finite element context, the contact interface is usually represented by a piecewise differentiable surface ...
Chamoret D., Rassineux A., Bergheau J. M.   +2 more
doaj   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

CONTACT PROBLEM ON TORSION OF TRANSVERSELY ISOTROPIC ELASTIC HALF-SPACE WITH INHOMOGENEOUS TRANSVERSELY ISOTROPIC COATING BY ROUND DIE

Advanced Engineering Research, 2013
An axisymmetric contact problem of the elasticity theory on the torsion of the transversely isotropic half-space with the inhomogeneous coating by the round die is considered.
Andrey Sergeyevich Vasilyev, Evgeny Valeryevich Sadyrin   +1 more
doaj  

A sensitivity analysis for frictionless contact problems

Computer Assisted Methods in Engineering and Science, 2023
A sensitivity analysis method for elasto-plastic contact problems with large deformation is developed based on two contact constraint methods, i.e., the Lagrange multiplier and penalty methods.
Xian Chen, Masahiko Mori, Toshiaki Hisada   +2 more
doaj  

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source