Results 101 to 110 of about 669,241 (267)

Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier   +6 more
wiley   +1 more source

Analysis on Operating Clearance of Matched Single Row Tapered Roller Bearings for Wind Turbine Main Shaft

open access: yes南方能源建设
[Introduction] The main shafting structure with double supports of single row tapered roller bearings has been widely used in wind turbines, and determining the appropriate bearing operating clearance is crucial for the reliable operation of bearings and
Zhongjie BU   +5 more
doaj   +1 more source

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song   +10 more
wiley   +1 more source

Review of modeling tool‒rock frictional contact with a blunt PDC cutter

open access: yesJournal of Intelligent Construction
The mechanisms of tool‒rock frictional contact are reviewed, with a focus on recent advances in numerical modeling. An idealized problem is defined for tool‒rock frictional contact with a rigid blunt tool sliding on the surface of a half-space.
Yaneng Zhou, George Z. Voyiadjis
doaj   +1 more source

Cognitive Behavioral Therapy for Youth With Childhood‐Onset Lupus: A Randomized Clinical Trial

open access: yesArthritis Care &Research, EarlyView.
Objective Our objective was to determine the feasibility and acceptability of the Treatment and Education Approach for Childhood‐Onset Lupus (TEACH), a six‐session cognitive behavioral intervention addressing depressive, fatigue, and pain symptoms, delivered remotely to individual youth with lupus by a trained interventionist.
Natoshia R. Cunningham   +29 more
wiley   +1 more source

Modeling and Finite-Element Performance Analysis of Selenol-Functionalized Carbon Nanotube/Natural Rubber Composites for Aircraft Tire Applications

open access: yesApplied Sciences
This study developed a natural rubber composite reinforced with selenol-functionalized carbon nanotubes, demonstrating significant mechanical enhancement.
Mingyao Xu   +5 more
doaj   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh   +5 more
wiley   +1 more source

Cleaning Capacity Analysis of Foam Pig in Submarine Pipeline

open access: yesShiyou jixie, 2018
Elliptical submarine pipeline may reduce the contact area with the pig and thus affect the sealing effect, resulting in inferior cleaning effect. To analyze the cleaning capacity of the foam pig in the submarine pipeline, taking the foam pig cleaning ...
Wei Yungang   +3 more
doaj  

Pain and Patient‐Reported Physical Function Did Not Differ Among Body Composition Profiles in Patients With Hip Osteoarthritis

open access: yesArthritis Care &Research, EarlyView.
Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan   +10 more
wiley   +1 more source

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