Results 51 to 60 of about 670,771 (266)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

A study on loaded tooth contact analysis of a cycloid planetary gear reducer considering friction and bearing roller stiffness

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2017
The cycloid planetary gear drives designed in the so-called RV-type play an important role in precision power transmission. Not only the high reduction ratio, but also the shock absorbability is the significant advantage.
Ching-Hao HUANG, Shyi-Jeng TSAI
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Contact Mechanics Analysis of Main Rotor Shaft Bearings in a Helicopter Main Gearbox Under Flight Load Spectrum

Lubricants
To investigate the contact mechanical performance of helicopter main gearbox rotor shaft bearings under a complex load spectrum, this study focuses on the contact stress and load-carrying characteristics of bearings operating under high-speed and heavy ...
Feng Zhang, Hongjian Wu, Yanan Zhang, Hongbin Liu, Baolin Jia, Xinlong Wu, Kun Zhao, He Liu, Wenhu Zhang   +8 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Evaluation of contact stress distribution on the surface of tibial insert component: Finite element analysis [PDF]

Songklanakarin Journal of Science and Technology (SJST)
The purpose of this study was to evaluate and compare the contact stress distributions on the surface of the tibial insert between the posterior-stabilized (PS) and cruciate-retaining (CR) total knee arthroplasty (TKA).
Techin Seechaipat, Supakit Rooppakhun, Chotchuang Phombut   +2 more
doaj  

Research on the Calculation Method for the Contact Stress of Wind Turbine Main Shaft Bearings Based on Finite Element Analysis

Lubricants
Under alternating loads, the contact situation for self-aligning roller bearings in the main shaft of a wind turbine is complex. Few methodologies exist for calculating the contact stress of main shaft bearings.
Yi Zou, Wenlei Sun, Hongwei Wang, Tiantian Xu, Bingkai Wang   +4 more
doaj   +1 more source

Finite Element Modeling of an Elderly Person’s Cornea and Rigid Gas Permeable Contact Lenses for Presbyopic Patients

Applied Sciences, 2018
Rigid gas permeable (RGP) contact lenses are a common presbyopic correction tool. However, many patients clinically need a long period of adaptation after wearing.
Han-Chao Chang, Ming-Ying Hsu, Wen-Tse Hsiao, Patrick Joi-Tsang Shum   +3 more
doaj   +1 more source