Results 61 to 70 of about 669,241 (267)
Design of straight bevel gear for pitting resistance [PDF]
FME Transactions, 2018 Based on the Tredgold geometric approximation, a transparent contact stress capacity model for straight bevel gears is presented. A bevel load factor is defined which provides a kinetic link between the physical bevel gear and virtual spur gear.
Osakue Edward E., Lucky Anetor
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
CONTACT NOTCH STRESS ASSESSMENT WITHIN FRICTIONAL CONTACT JOINTS
Dyna, 2012 En el artículo se analizan, por medio del método del elemento finito (FE), las concentraciones de esfuerzo en los límites de zonas de contacto nominales que incluyen deslizamiento con fricción. Los elementos mecánicos para el análisis numérico se consideran como una flecha acoplada a un cubo de rueda por medio de aros cónicos deformables. El proceso de
SZWEDOWICZ, DARIUSZ, BEDOLLA, JORGE
openaire +3 more sources
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Contact Analysis and Structural Improvement of the Swivel Joints in High Pressure Manifold
Shiyou jixie, 2018 During the operation of the swivel joint in the oilfield, pitting and obvious indentation of the ball bearing at the joint were observed and affected its operation.
Guo Dengming, Wang Sui, Bian Heman
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Optimal Design of Spur Gears With Increased Contact Ratio
Journal of Mechanical EngineeringThe study is devoted to optimal design of gears with profile contact ratio εα ≥ 2. Optimality criteria formulated as follows: the contact stresses in the pitch point must take a minimum value when all constraints are met, first, when the profile contact ...
Ustynenko Oleksandr +6 more
doaj +1 more source
Contact Characteristics of Active Elbow in High-Pressure Manifold
Shiyou jixie, 2022 In order to investigate the raceway pitting corrosion of the active elbow in high-pressure manifold in oil and gas fields,a large-diameter active elbow of Model 130.2 mm-105 MPa(5 1/8 in-15 000 psi)was taken as an example to investigate the influences of
Zhang Guoyou
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