Results 61 to 70 of about 1,605,312 (259)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
ELECTROMAGNETIC POLARIZED SWITCH WITH BOUNCE-FREE CONTACT SYSTEM
Надежность и качество сложных системBackground. Electromagnetic polarized switches are used in land-based vehicles to commutate the electric circuits in a system. There is a wide variety of industrially available commutating devices, but few of them are applicable for the above purpose due
Vladimir N. Kitaev +4 more
doaj +1 more source
Contact Melting in Simple Eutectic System
EPJ Web of Conferences, 2011 The growth of the liquid interlayer in the system lead-tin at 463 K is studied experimentally in the nonstationary diffusion process of contact melting. The contact melting was carried out between pure tin and solid solution of tin in lead (0, 5.9, 11.5,
Anokhina N. N. +2 more
doaj +1 more source
Contamination-free non-contact wettability assessment system
ROBOMECH Journal, 2017 Surface wettability is one of most important indexes for understanding the interfacial characteristics between a solid surface and a liquid, especially such physico-chemical properties as hydrophilicity and water repellency.
Nobuyuki Tanaka +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
THE SYSTEM OF CONTACT SYSTEM POWER SUPPLY OF DC NETWORK WITH A LONGITUDINAL LINE OF HIGH VOLTAGE
Nauka ta progres transportu, 2008 The power supply system of a contact network using a longitudinal line with points of communication without transformer is considered. The approach allowing to facilitate power filters and the way of switching of in-series connected semiconductor ...
Yu. P. Honcharov +6 more
doaj
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Polarization of contact forces in multi-contact systems
European Journal of Computational Mechanics, 2010 The aim of this study is to identify the homogenized laws modeling the overall behaviour of multi-contact systems. At the moment, these systems are generally analyzed either by continuum mechanics or micro-mechanics and a multi-scale approach. These approaches differ from the phenomenological approach traditionally used for modeling the behavior of ...
Dumont, Serge +2 more
openaire +3 more sources