Results 61 to 70 of about 150,874 (288)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Reliable smart energy IoT-cloud service operation with container orchestration

, 2017
We discuss the prototype implementation of IoT-Cloud services for efficient cooling management for small-size server room. We leverage open-source-based miniaturized playground for IoT-Cloud services and realize smart energy IoT-Cloud service based on ...
KIM, JONG WON, Seungryong Kim, Kim, Seungryong, Kim, Chorwon, Chorwon Kim, JongWon Kim   +5 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

CONTAINER TRANSPORTATION NETWORK EQUILIBRIUM ANALYSIS CONSIDERING DRAFT OF VESSEL [PDF]

, 2007
This paper analyzes container transportation network equilibrium considering draft of vessels. Concept of load factor ( ) of ship is included in the model. Three players are considered, i.e.
Syafi’i, -
core  

Prompt-Driven and Kubernetes Error Report-Aware Container Orchestration

Future Internet
Background: Container orchestration systems like Kubernetes rely heavily on declarative manifest files, which serve as orchestration blueprints.
Niklas Beuter, André Drews, Nane Kratzke   +2 more
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

A Container-based platform for multi - cloud application orchestration

, 2020
Multi-cloud applications are becoming popular, as they can run across multiple public and private cloud platforms while overcoming vendor lock-in, reducing cost, and enhancing flexibility and reliability.
Adikari AMAS
core   +1 more source

Mixed-Runtime Pod Networking for Kubernetes-Based Edge Computing

IEEE Access
In recent years, microservice-based applications have shifted towards cloud-edge computing, taking advantage of green energy, lower latencies, and local computational resources.
Tom Goethals, Miel Verkerken, Merlijn Sebrechts, Filip De Turck, Bruno Volckaert   +4 more
doaj   +1 more source