Results 71 to 80 of about 137,495 (298)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Risk Assessment of Work Accident in Container Terminals Using the Fault Tree Analysis Method

open access: yesJournal of Marine Science and Engineering, 2020
The use of containers in the world is increasing every year in line with international trade flows. In very complex container terminal operations, the risk of work accidents is inevitable and can happen at any time.
Muhammad Arif Budiyanto, Haris Fernanda
doaj   +1 more source

A Key to Container-Breeding Mosquitoes of Michigan (Diptera: Cllllcidae), With Notes on Their Biology [PDF]

open access: yes, 2017
An illustrated key to larvae and notes on the biology of container-breeding mosquitoes of Michigan are presented. Two species included in the key. Aedes aegypti and Aedes albopictus.
Merritt, Richard W   +2 more
core   +3 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Participation of Private Investors in Container Terminal Operation: Influence of Global Terminal Operators

open access: yesAsian Journal of Shipping and Logistics, 2015
Private container terminal operators have begun to participate in the port business in Asia since the late 1980s. Terminal operators decide whether to invest in terminal infrastructures, and the enhancement of the quality of service level.
Heejung YEO
doaj   +1 more source

Off-peak truck deliveries at container terminals: the 'Good Night' program in Israel [PDF]

open access: yes, 2016
Purpose – Avoiding truck congestion and peaks in landside activity is one of the challenges to container terminal managers. The spreading of truck arrivals at terminals can be facilitated by widening the opening hours of terminals at the landside. Israel’
Bentolila, David   +3 more
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

A decision support tool for container terminal optimization within the berth subsystem

open access: yesTransport, 2016
The article deals with a current problem faced by all ports: how to enable container terminals to keep up with the development of container ships, which, due to economies of scale, are constantly increasing in size.
Maja Stojaković, Elen Twrdy
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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