Results 151 to 160 of about 185,405 (315)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
v, 14 p.The WHO regional meeting on poliovirus containment progress for national poliovirus containment coordinators and national authorities for containment, held on 26–27 September 2023, provided technical support in the field of poliovirus containment
World Health Organization. Regional Office for Europe
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Investigación y Educación en Enfermería, 2007 Objetivo: Verificar la efectividad de la contención en el tiempo de recuperación de la hipoxia percutánea de neonatos prematuros con Síndrome de Dificultad Respiratoria, posterior a la aspiración con y sin bolsa de oxígeno pre-aspiración.
Bertha Cecilia Salazar González +4 more
doaj
Im/Material Traces from Within Ireland's Culture of Containment
, 2012 Im/material Traces is a photographic exhibition that captures the im/material traces of lives once lived in the Ireland’s vast network of state funded and religious run institutions. Images of this ‘architecture of containment’ include former Magdalen
Greene, Kellie (S28357), Greene, Kellie
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Nuclear Power Plant Containment Pressure Boundary Research
, 1999 Research to address aging of the containment pressure boundary in light-water reactor plants is summarized. This research is aimed at understanding the significant factors relating occurrence of corrosion, efficacy of inspection, and structural capacity ...
Cherry, J. L. +4 more
core