Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Eliminating Seclusion Use for Women in Secure Forensic Hospitals. Are We Doing Enough to Consider Sex and Gender Differences for Elimination? [PDF]
Hansen A.
europepmc +1 more source
Transient analysis of a flywheel battery containment during a full rotor burst event.
B.J. Hsieh
openalex +1 more source
Evaluation of beta-propiolactone and AVL-ethanol inactivation protocols for highly pathogenic avian influenza virus in allantoic fluid and cell culture. [PDF]
Pessoa N +5 more
europepmc +1 more source
A framework for evaluating biosafety and biosecurity in national network of biosafety level-3 laboratories in India: an initiative under national one health mission. [PDF]
Patil DY +13 more
europepmc +1 more source
Controlled Containment, Radioactive Waste Management in the Netherlands
Hans D.K. Codee
openalex +1 more source
MPOX transmission risks and biosafety protocols in laboratory animal research. [PDF]
Ayoola MA +6 more
europepmc +1 more source
Elasto-Piastic Analysis of Nozzle Intersections in Reactor Containments
J.M. Sättele +2 more
openalex +1 more source

