Results 31 to 40 of about 853,364 (298)
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
UVC-Mirror for effective pathogens inactivation in air ducts [PDF]
Improving the air quality of indoor environments (IAQ) is of utmost importance to safeguard public health as people spend about 80–90% of their time indoor. Efficient Ultraviolet germicidal irradiation (UVGI) system represents a strategic and sustainable
Treccani Laura +12 more
doaj +1 more source
Wheat–maize rotation is one of the most popular systems and successful intensification cropping systems in Northern China, while soils in some of this area are contaminated by cadmium (Cd). However, few studies have performed experiments on the reduction
Yu Dun +8 more
doaj +1 more source
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Once petroleum hydrocarbons (PHs) are released into the soil, the interaction between PHs and soil media is dependent not only upon the soil properties but also on the characteristics of PHs.
Liang Wang +6 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Cadmium (Cd) has seriously threatened the safe production of food crops. Passivator amendments are commonly used to control the soil Cd availability. Yet, few studies are tested to explore the effect of the combination of various amendments.
Zehui Niu +4 more
doaj +1 more source
Advancement in utilization of magnetic catalysts for production of sustainable biofuels
In this study, we summarize recent advances in the synthesis of magnetic catalysts utilized for biodiesel production, particularly focusing on the physicochemical properties, activity, and reusability of magnetic mixed metal oxides, supported magnetic ...
Yutao Zhang +10 more
doaj +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source

