Results 31 to 40 of about 65,095 (302)
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Image Retrieval Berdasarkan Fitur Warna, Bentuk, dan Tekstur
ComTech, 2014 Along with the times, information retrieval is no longer just on textual data, but also the visual data. The technique was originally used is Text-Based Image Retrieval (TBIR), but the technique still has some shortcomings such as the relevance of the ...
Rita Layona +2 more
doaj +1 more source
IEEE Access, 2022 With the rapid advancement of medical imaging technologies, the high-resolution CT image data is becoming increasingly valuable for both medical research and clinical diagnosis. The paper takes lung CT image as an example.
Yi Zhuang, Nan Jiang, Shuai Chen
doaj +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Interactive Content Based Image Retrieval using Multiuser Feedback
JOIV: International Journal on Informatics Visualization, 2017 Retrieving images from large databases becomes a difficult task. Content based image retrieval (CBIR) deals with retrieval of images based on their similarities in content (features) between the query image and the target image.
M. Premkumar, R. Sowmya
doaj +1 more source
Combined global and local semantic feature–based image retrieval analysis with interactive feedback
Measurement + Control, 2020 Nowadays, user expects image retrieval systems using a large database as an active research area for the investigators. Generally, content-based image retrieval system retrieves the images based on the low-level features, high-level features, or the ...
A Anandh, K Mala, R Suresh Babu
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
İçerik Tabanlı Görüntü Erişimi / Content-Based Image Retrieval
Bilgi Dünyası, 2005 Digital image collections are expanding day by day, and image retrieval becomes even harder. Both individuals and institutions encounter serious problems when building their image archives and later when retrieving the archived images. Visual information
İrem Soydal, Umut Al, Umut Sezen
doaj
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source