Results 181 to 190 of about 4,382,039 (223)

Development of InDel markers associated with leaf protein content in mulberry based on whole-genome resequencing. [PDF]

PLoS One
Li J, Shen Z, Zhang Q, Shi J, Jia F, Liu Y, Luo H, Zhang R.   +7 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Quality and reliability of semaglutide content on different Chinese short video platforms: a study focusing on side effects. [PDF]

Front Public Health
Song J, He X, Cui Z, Sun Y, Liu Y, Yu H, Li A, Jin M.   +7 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Reduced Hospital Incidence of Autoimmune Encephalitis During the COVID-19 Pandemic. [PDF]

Neurol Neuroimmunol Neuroinflamm
Wickel J, Chung HY, Konen FF, Rössling R, Bertolini A, Kraft A, Siebenbrodt K, Bittner S, Juranek A, Brokbals M, Räuber S, Klausewitz J, Pfeffer LK, Scherag A, Menge T, Finke A, Doppler K, Urbanek C, Bien CG, Seifert-Held T, Hoffmann F, Wandinger KP, Tauber SC, Süße M, Lewerenz J, Madlener M, Rostasy K, Prüss H, Sühs KW, Kümpfel T, Thaler FS, Leypoldt F, Geis C, GENERATE study group.   +33 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Cat content!

Archivalia, 2010
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Harnessing faba bean MAGIC populations for enhanced protein content, yield, and agronomic performance in diverse environments. [PDF]

Front Plant Sci
Abou Khater L, Maalouf F, Walker C, Bouhlal O, Aloui K, Balech R, Mahmoudi KE, Ibriz M, Ogbonnaya FC, Kumar S.   +9 more
europepmc   +1 more source