Results 181 to 190 of about 23,935,082 (334)
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Tuning starch granule size distributions in durum wheat using genetic variation at a single locus. [PDF]
Theor Appl GenetFahy B, Chen J, Seung D.
europepmc +1 more source
Measuring soil water content and evaporation by the neutron scattering method.
, 1956 J. W. Holmes
openalex +2 more sources
Nucleic Acid Content of Petkus Rye Embryos in Relation to Vernalization and Devernalization [PDF]
, 1956 LR Finch, D. J. Carr
openalex +1 more source
A scalable content-addressable network
Conference on Applications, Technologies, Architectures, and Protocols for Computer Communication, 2001 Sylvia Ratnasamy +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Biological value of herring-meal protein. Urinary nitrogen excretion in relation to protein content of diet and food intake [PDF]
, 1959 Leif Rein Njaa
openalex +1 more source
Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source