Results 261 to 270 of about 19,398,290 (317)
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
Phytochemical and biological characterization of extracted natural colors from fruits of monotheca buxifolia. [PDF]
Khan S+6 more
europepmc +1 more source
FURTHER STUDIES OF THE CALCIUM CONTENT OF THE BODY AS INFLUENCED BY THAT OF THE FOOD
Caroline Sherman Lanford, H. C. Sherman
openalex +1 more source
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
The Effect of Osmotic Dehydration Conditions on the Magnesium Content in Beetroot (<i>Beta vulgaris</i> L.). [PDF]
Kulczyński B+5 more
europepmc +1 more source
A METHOD TO DETERMINE THE CARBON DIOXIDE CONTENT OF MUSCLE
John Ferguson, Laurence Irving
openalex +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
The effects of flipped classroom and jigsaw teaching strategies on learning, retention of course content, and satisfaction among nursing students: a quasi-experimental study. [PDF]
Khodadadeh A, Rivaz M, Torabizadeh C.
europepmc +1 more source