Results 51 to 60 of about 85,426 (286)

Protein carbonyl group content in patients affected by familiar chronic nail candidiasis [PDF]

open access: yesMediators of Inflammation, 2003
Familiar chronic nail candidiasis (FCNC) is a rare disorder characterized by early‐onset infections caused by different species of Candida, restricted to the nail of the hands and feet, and associated with a low serum concentration of intercellular adhesion molecule 1.
GANGEMI, Sebastiano   +10 more
openaire   +4 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Interpreters, rapport, and the role of familiarity [PDF]

open access: yes, 2021
Rachel Mapson - ORCID: 0000-0003-0400-6576 https://orcid.org/0000-0003-0400-6576This paper explores one of the conditions that can foster interpreters’ ability to process meaning: their familiarity with the primary participants.
Mapson, Rachel, Major, George
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Enhancing Scientific Literacy in the Undergraduate Cell Biology Laboratory Classroom

open access: yesJournal of Microbiology & Biology Education, 2016
This paper describes the implementation of the Scientific Literacy in Cell Biology (SLCB) curriculum in an undergraduate biology laboratory course.
Hadiya Woodham   +4 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Long-Term Knowledge Retention of Biochemistry Among Medical Students in Riyadh, Saudi Arabia: Cross-Sectional Survey

open access: yesJMIR Medical Education
BackgroundBiochemistry is a cornerstone of medical education. Its knowledge is integral to the understanding of complex biological processes and how they are applied in several areas in health care.
Nimer Mehyar   +7 more
doaj   +1 more source

Mondegreens and Soramimi as a method to induce misperceptions of speech content--influence of familiarity, wittiness, and language competence. [PDF]

open access: yesPLoS ONE, 2014
Expectations and prior knowledge can strongly influence our perception. In vision research, such top-down modulation of perceptual processing has been extensively studied using ambiguous stimuli, such as reversible figures.
Claudia Beck   +2 more
doaj   +1 more source

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