Results 71 to 80 of about 6,117,480 (275)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

The influence of advertisement familiarity and originality on visual attention and brand memory. [PDF]

Based on Mandler's theory of schema organization and previous visual attention research, we formulate and test hypotheses about the impact of ad familiarity and ad originality on attention and memory for print advertisements. To that end, one hundred and
Pieters, R, Warlop, Luk, Wedel, M
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Recognition-Based and Familiarity-Based Portfolio Strategies - An Experimental Study [PDF]

Empirical evidences show that investors tend to be biased toward investing in domestic (home bias) and local (local bias) stocks. Familiarity is considered to be one of the reasons. A similar concept was proposed by Goldstein and Gigerenzer (1999, 2002),
Linan Diao
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

I Value It, but I Don’t Use It: Attitudes Toward Fact-Checking Among Portuguese University Students

Journalism and Media
Fact-checking appeared as one of the responses to disinformation, establishing itself inside the journalism profession as another of its ethos. However, its social relevance relies on public perception and engagement. Despite growing evidence of approval,
João Pedro Baptista, Francisco Conrado, Pedro Costa Rodrigues   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Dissociating recollection from familiarity: electrophysiological evidence that familiarity for faces is associated with a posterior old/new effect [PDF]

, 2007
In recognition memory research, a tension exists between dual-process and single-process models of episodic retrieval. Dual-process models propose that ‘familiarity’ assessment and the ‘recollection’ of contextual information are independent processes ...
Donaldson, David, MacKenzie, Graham, Donaldson, David I.   +2 more
core   +1 more source

Kesesuaian teks dwibahasa Jawa-Indonesia jenjang B1 terhadap pedoman perjenjangan nomor 030/P/2022

Diglosia
The need for children's literature that aligns with developmental stages and integrates cultural values is increasingly urgent to support contextual literacy.
Mulasih Mulasih, Suroso Suroso, Anwar Efendi   +2 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source