Results 71 to 80 of about 5,341,789 (273)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Familiarity breeds content: The impact of exposure to change on employee openness and well‐being

Journal of Occupational and Organizational Psychology, 2002
This article describes a longitudinal study of how openness to change, job satisfaction, anxiety and depression are affected by exposure to a change situation ‐ in this case, the implementation of new technology and work practices. Measures were taken before the change was fully implemented and again several months later. Employees
Axtell, C., Wall, T., Stride, C.B., Pepper, K., Clegg, C., Gardner, P., Bolden, R.   +6 more
openaire   +2 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Complementing but Not Replacing: Comparing the Impacts of GPT-4 and Native-Speaker Interaction on Chinese L2 Writing Outcomes

Behavioral Sciences
This study explored the efficacy of large language models (LLMs), namely GPT-4, in supporting second language (L2) writing in comparison with interaction with a human language partner in the pre-writing phase.
Zhaoyang Shan, Zhangyuan Song, Xu Jiang, Wen Chen, Luyao Chen   +4 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Culturally responsive assessment in mathematical word problems and numerical cognition in multilingual education

Scientific Reports
In multilingual education systems, the cultural disconnect between students’ lived experiences and assessment content can significantly hinder both comprehension and performance, especially in mathematics.
Simon Ntumi, Saba Nixon Adzifome, Theophilus Nyamekye, Foster Kwame Vedor   +3 more
doaj   +1 more source

Social Media Ban for Children and Its Influencing Factors: Evidence from an Opinion Cross-Sectional Study in Greece

Social Sciences
Several countries have adopted a nationwide ban on social media access for children. Our aim was to investigate public opinion regarding the implementation of a social media ban for children, as well as the factors influencing these views.
Petros Galanis, Aglaia Katsiroumpa, Ioannis Moisoglou   +2 more
doaj   +1 more source

Team member familiarity and team effectiveness in the operating room: The mediating effect of mutual trust and shared mental models.

Surgery
BACKGROUND Teamwork in the operating room is of paramount importance to provide high-quality patient care. It has been shown that increased team member familiarity predicts improved teamwork. A complicating factor is the often-changing composition of the
Tessa L. Verhoeff, J. Janssen, R. Hoff
semanticscholar   +1 more source