Results 91 to 100 of about 5,341,789 (273)

Detecting Artificial Intelligence–Generated Versus Human-Written Medical Student Essays: Semirandomized Controlled Study

JMIR Medical Education
BackgroundLarge language models, exemplified by ChatGPT, have reached a level of sophistication that makes distinguishing between human- and artificial intelligence (AI)–generated texts increasingly challenging.
Berin Doru, Christoph Maier, Johanna Sophie Busse, Thomas Lücke, Judith Schönhoff, Elena Enax- Krumova, Steffen Hessler, Maria Berger, Marianne Tokic   +8 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Preparation for the Implementation of the International Classification of Diseases 11th Revision: A Survey on Clinical Coders' Knowledge of the International Classification of Diseases 11th Revision, Educational Needs, and Readiness to Accept New Roles: A Cross‐Sectional Study

Health Science Reports
Background and Aims Studies have shown that the knowledge and skills of clinical coders impact the quality of clinical coding, and professional training for clinical coders is essential to ensure coding quality.
Javad Zarei, AliMohammad Hadianfard, Abbas Sheikhtaheri   +2 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Exploring fake news awareness and trust in the age of social media among university student TikTok users

Cogent Social Sciences
This study explores the awareness of fake news and trust dynamics among University students on TikTok. Utilizing qualitative research through semi-structured interviews with University students in Vietnam, the findings reveal a generally acknowledged ...
Duong Hoai Lan, Tran Minh Tung
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Using podcasts to bridge the gap between science communication and specialized scientific fields: a case study of mass spectrometry

Frontiers in Communication
This study aimed to evaluate the use of podcasts in disseminating specialized scientific fields, such as mass spectrometry. Four podcasts featuring interviews with researchers working with mass spectrometry were produced.
Nayyer Rehman, Nayyer Rehman, Victoria Edkins, Nives Ogrinc, Nives Ogrinc   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The integration of 21st century skills in the curriculum of education

Heliyon
The premise of this study, utilizing content analysis and descriptive qualitative designs, posited that teachers' comprehension of 21st-century/4Cs skills' could define the caliber of educational materials in higher education institutions.
Herlinawati Herlinawati, Marwa Marwa, Noriah Ismail, Junaidi, Ledya Oktavia Liza, Dominikus David Biondi Situmorang   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source