Results 91 to 100 of about 4,786,818 (328)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
TARGE: large language model-powered explainable hate speech detection [PDF]
PeerJ Computer ScienceThe proliferation of user-generated content on social networking sites has intensified the challenge of accurately and efficiently detecting inflammatory and discriminatory speech at scale. Traditional manual moderation methods are impractical due to the
Muhammad Haseeb Hashir +2 more
doaj +2 more sources
The struggle for sentencing reform : will the English guidelines model spread? [PDF]
, 2013 Are closely comparable countries following the path forged by England and Wales by moving towards the development of systematic sentencing guidelines by a Sentencing Council?
Tata, Cyrus
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
A Misogynistic Glitch? A Feminist Critique of Algorithmic Content Moderation
Law, Technology and HumansIn recent years, all leading social media platforms have integrated artificial intelligence (AI) into their content moderation workflows. An increasingly prevalent narrative suggests that algorithms capable of detecting and removing prohibited or harmful
Valentina Golunova
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Tackling the spread of disinformation Why a co-regulatory approach is the right way forward for the EU. Bertelsmann Stiftung Policy Paper 12 December 2019 [PDF]
, 2019 In recent years social media platforms have led to an unprecedented increase in the spread of disinformation. Concerns about these new and dynamic ways to spread falsehoods have brought politicians and regulators onto the stage. In this paper Paul-Jasper
Dittrich, Paul-Jasper
core
How to promote informal learning in the workplace? The need for incremental design methods
, 2017 Informal Learning in the Workplace (ILW) is ensured by the everyday work activities in which workers are engaged. It accounts for over 75 per cent of learning in the workplace.
Marty, Jean-Charles +2 more
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Content moderation assistance through image caption generation
Intelligent Systems with ApplicationsThe rapid growth in digital media creation has led to an increased challenge in content moderation. Manual and automated moderation are susceptible to risks associated with a slower response time and false positives arising from unpredictable user inputs
Liam Kearns
doaj +1 more source