Results 81 to 90 of about 5,435,112 (248)

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Legal Mechanisms for Digital Content Moderation on HR Tech Platforms

open access: yesЦифровое право
This essay examines the legal mechanisms of digital content moderation on HR tech platforms as an integral element of contemporary regulation of the digital labor market. In the context of digital transformation, online platforms increasingly move beyond
S. E. Shabronova
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

The Heteronormative Male Gaze: Experiences of Sexual Content Moderation Among Queer Instagram Users in Berlin

open access: yesInternational Journal of Communication
Recent research suggests that social media moderation policies banning sexual content systematically disfavor LGBTQIA+ people. However, specific impacts on particular communities remain understudied.
Rachel Griffin
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Content Moderation in Online Platforms [PDF]

open access: yes
A critical role of online platforms like Facebook, Wikipedia, YouTube, Amazon, Doordash, and Tinder is to moderate content. Interventions like banning users or deleting comments are carried out thousands of times daily and can potentially improve our ...
Horta Ribeiro, Manoel
core   +1 more source

Fediverse Blocklists: Moderation in Noncapitalist Social Media

open access: yestripleC: Communication, Capitalism & Critique
Content moderation is a key form of labour on social media. While much of the scholarly attention has been given to paid or voluntary content moderation on corporate social media, this paper draws attention to content moderation on noncapitalist ...
Robert W Gehl
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Algorithmic Arbitrariness in Content Moderation [PDF]

open access: yes
Machine learning (ML) is widely used to moderate online content. Despite its scalability relative to human moderation, the use of ML introduces unique challenges to content moderation.
Machado, Caio Vieira   +3 more
core   +1 more source

Reasoning about Political Bias in Content Moderation

open access: yes, 2020
Content moderation, the AI-human hybrid process of removing (toxic) content from social media to promote community health, has attracted increasing attention from lawmakers due to allegations of political bias.
Robertson, Ronald E.   +2 more
core   +1 more source

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