Results 61 to 70 of about 39,629 (284)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

How to co-create content moderation policies: the case of the AutSPACEs project

open access: yesData & Policy
The moderation of user-generated content on online platforms remains a key solution to protecting people online, but also remains a perpetual challenge as the appropriateness of content moderation guidelines depends on the online community that they aim ...
Georgia Aitkenhead   +11 more
doaj   +1 more source

Do Not Use This Hashtag: Fat Acceptance (Mis)information and Discursive Boundary-Work as Content Moderation on Instagram

open access: yesInternational Journal of Communication, 2023
The discussions concerning the use of #fatacceptance on Instagram are important for observing both the limitations of official content moderation on social media platforms and an emerging group of users who engage in unofficial content moderation through
Melissa Zimdars
doaj  

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Online Extremism, AI, and (Human) Content Moderation

open access: yesFeminist Philosophy Quarterly, 2022
This paper has three main goals: (1) to clarify the role of artificial intelligence (AI)—along with algorithms more broadly—in online radicalization that results in “real world violence,” (2) to argue that technological solutions (like better AI) are ...
Michael Randall Barnes
doaj  

Chillbot: Content Moderation in the Backchannel

open access: yesProceedings of the ACM on Human-Computer Interaction
Moderating online spaces effectively is not a matter of simply taking down content: moderators also provide private feedback and defuse situations before they cross the line into harm. However, moderators have little tool support for these activities, which often occur in the backchannel rather than in front of the entire community.
Joseph Seering   +5 more
openaire   +2 more sources

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Content Moderation Regulation as Legal Role-Scripting

open access: yes
Lawmakers and scholars concerned with content moderation regulation typically appeal to “analogies” to justify or undermine different forms of regulation.
Mazzurco, Sari
core   +5 more sources

Pengutan Moderasi Beragama Berbasis Konten pada Organisasi IPNU-IPPNU

open access: yesKifah
Religious moderation is an important principle in maintaining social harmony that emphasizes balance, tolerance, and respect for differences amid religious and cultural diversity in Indonesia.
Siti Asiyah
doaj   +1 more source

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