Results 41 to 50 of about 39,629 (284)

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Who Can Say What? Testing the Impact of Interpersonal Mechanisms and Gender on Fairness Evaluations of Content Moderation

Social Media + Society
Content moderation is commonly used by social media platforms to curb the spread of hateful content. Yet, little is known about how users perceive this practice and which factors may influence their perceptions. Publicly denouncing content moderation—for
Ina Weber, João Gonçalves, Gina M. Masullo, Marisa Torres da Silva, Joep Hofhuis   +4 more
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Content Moderation and the Quest for Democratic Legitimacy

Weizenbaum Journal of the Digital Society, 2022
The paper analyzes the public controversy incited by the introduction of the Network Enforcement Act (NetzDG) in Germany. This law obliges social media platforms to delete unlawful content from their sites and has received international attention as a ...
Laura Fichtner
doaj   +1 more source

A Trade-off-centered Framework of Content Moderation

, 2022
Content moderation research typically prioritizes representing and addressing challenges for one group of stakeholders or communities in one type of context.
Nie, Peipei, Brubaker, Jed R., Jiang, Jialun Aaron, Fiesler, Casey   +3 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The Urgency of Religious Moderation in Preventing Radicalism in Indonesia

Esensia: Jurnal Ilmu-Ilmu Ushuluddin, 2020
This paper aims to contribute to the thought of realizing religious moderation to prevent radicalism. The problem is, what is meant by religious moderation and how to do the deradicalization of religious moderation based harmony in Indonesia.
Arifinsyah Arifinsyah, Safria Andy, Agusman Damanik   +2 more
doaj   +1 more source

(In)visible moderation: A digital ethnography of marginalized users and content moderation on Twitch and Reddit

, 2022
Research suggests that marginalized social media users face disproportionate content moderation and removal. However, when content is removed or accounts suspended, the processes governing content moderation are largely invisible, making assessing ...
Haimson, Oliver L., Delmonaco, Daniel, Mayworm, Samuel, Thach, Hibby   +3 more
core   +1 more source