Results 81 to 90 of about 525,022 (337)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Stadtentwicklung durch Auszeichnung — der Städtewettbewerb T-City
The article discusses city contests as an instrument of urban development. It describes different forms of city contests and shows, how those correspond with different interests and expectations of the contractee and the participating cities ...
Michael Lobeck +2 more
doaj +1 more source
Weight change among repeat participants of an Aboriginal community-based weight loss program
Background Community-based weight loss programs may have potential to address overweight and obesity at the population level. However, participation patterns and individual outcomes from these programs are understudied.
Erika Bohn-Goldbaum +7 more
doaj +1 more source
Incentives in Contests with Heterogeneous Solvers
In a contest in which heterogeneous solvers make effort to develop solutions, existing theories predict different outcomes about how solvers will change their effort levels as more participants compete for a prize.
Ersin Körpeoğlu, Soo-Haeng Cho
semanticscholar +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Feess, E. +2 more
openaire +3 more sources
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
An Analysis of the Influence of Graph Theory When Preparing for Programming Contests
The subject known as Programming Contests in the Bachelor’s Degree in Computer Engineering course focuses on solving programming problems frequently met within contests such as the Southwest Europe Regional Contest (SWERC).
Cristina Jordán +2 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Local newspaper movie contests and the creation of the first movie fans
This article explores the advent of local newspaper movie contests in the 1910s and how these contests helped to create active movie fans. Such contests increased the popularity of the new medium of film by engaging local audiences in the process of ...
Jessica Leonora Whitehead
doaj +1 more source

