Results 101 to 110 of about 319,282 (309)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Competition amongst contests [PDF]

open access: yes
This article analyses the allocation of prizes in contests. While existing models consider a single contest with an exogenously given set of players, in our model several contests compete for participants.
Ghazala Azmat, Marc Möller
core  

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Contesting Resources - Rent Seeking, Conflict and the Natural Resource Curse [PDF]

open access: yes
A growing empirical literature links natural resource abundance and "pointiness" to impeded economic growth and civil strife. We develop rent seeking and conflict models that capture the most salient features of contests for resource rents, and show how ...
Bulte, Erwin, Wick, Katharina
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Are daily fantasy sports gambling?

open access: yesJournal of Sports Analytics, 2019
Millions of people play daily fantasy sports in the hopes of winning money. The two largest daily fantasy sports companies, FanDuel ® and DraftKings ® process billions of dollars in entry fees every year.
Todd Easton, Sarah Newell
doaj   +1 more source

Self assessment in insects: honeybee queens know their own strength.

open access: yesPLoS ONE, 2008
Contests mediate access to reproductive opportunities in almost all species of animals. An important aspect of the evolution of contests is the reduction of the costs incurred during intra-specific encounters to a minimum.
Vincent Dietemann   +8 more
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Truth Contests and Talking Corpses [PDF]

open access: yes, 1999
In diverse fictions from the second century Roman Empire, two parties with competing claims to truth hold a formal contest in a public place where, after a series of abrupt reversals, the issue is finally decided by the evidence of a dead, mutilated, or
Gleason, Maud
core  

Lobbying contests with endogenous policy proposals [PDF]

open access: yes, 2005
Lobbyists choose what to lobby for. If they can precommit to certain policy proposals, their choice will have an influence on the behavior of opposing lobbyists.
Münster, Johannes
core   +3 more sources

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