Results 111 to 120 of about 319,282 (309)

Merger in Contests [PDF]

open access: yes
Competition in some markets is a contest. This paper studies the merger incentives in such markets. Merger can be profitable. The profitability depends on the post-merger contest st ructure, the discriminatory power of the contest and on the number of ...
Kai A. Konrad   +2 more
core  

Gambling in contests with regret [PDF]

open access: yes, 2013
This paper discusses the gambling contest introduced in Seel & Strack (Gambling in contests, Discussion Paper Series of SFB/TR 15 Governance and the Efficiency of Economic Systems 375, Mar 2012.) and considers the impact of adding a penalty associated ...
Feng, Han, Hobson, David
core  

Build It, Break It, Fix It: Contesting Secure Development

open access: yes, 2016
Typical security contests focus on breaking or mitigating the impact of buggy systems. We present the Build-it Break-it Fix-it BIBIFI contest which aims to assess the ability to securely build software not just break it.
Hicks, Michael   +5 more
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Gender and Programming Contests: Mitigating Exclusionary Practices

open access: yesInformatics in Education, 2006
Individuals vary across many dimensions due to the effects of gender-based, personality, and cultural differences. Consequently, programming contests with a limited and restrictive structure (e.g., scoring system, questioning style) are most favourable ...
Maryanne FISHER, Anthony COX
doaj   +1 more source

Emotions in Litigation Contests [PDF]

open access: yes
This paper introduces the concept of emotions into the standard litigation contest. Positive (negative) emotions emerge when litigants win (lose) at trial and are dependent in particular on the level of defendant fault.
Florian Baumann, Tim Friehe
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Contests with multi-tasking [PDF]

open access: yes
The standard contest model in which participants compete in a single dimension is well understood and documented. Multi-dimension extensions are possible but are liable to increase the complexity of the contest structure, mitigating one of its main ...
Clark, Derek, Konrad, Kai A.
core   +3 more sources

Semi-Public Contests [PDF]

open access: yes
The process of innovation is driven by two main factors: new inventions and institutions supporting the transformation of inventions into marketable innovations.
Prüfer, J.
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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