Results 211 to 220 of about 4,666,149 (260)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
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Evaluation & the Health Professions, 2003
This article provides an analysis of the way in which placebo effects could be investigated and taken into account, supported by a description of some of the major articles that have been published on this topic. Based on conceptual, theoretical, and methodological issues, the authors highlight some of the reasons for current controversies regarding ...
Zelda, Di Blasi, Jos, Kleijnen
openaire +2 more sources
This article provides an analysis of the way in which placebo effects could be investigated and taken into account, supported by a description of some of the major articles that have been published on this topic. Based on conceptual, theoretical, and methodological issues, the authors highlight some of the reasons for current controversies regarding ...
Zelda, Di Blasi, Jos, Kleijnen
openaire +2 more sources
Information Knowledge Systems Management, 2011
Complexity should be at the heart of any viable theory of causation. Without it, we cannot give a sensible account of the importance of context. With many causal factors in play, jointly producing an effect, we come to understand the context-sensitive nature of causation.
Mumford, Stephen, Anjum, Rani Lill
openaire +1 more source
Complexity should be at the heart of any viable theory of causation. Without it, we cannot give a sensible account of the importance of context. With many causal factors in play, jointly producing an effect, we come to understand the context-sensitive nature of causation.
Mumford, Stephen, Anjum, Rani Lill
openaire +1 more source
Context effects as auditory contrast
Attention, Perception, & Psychophysics, 2014Three experiments are reported that collectively show that listeners perceive speech sounds as contrasting auditorily with neighboring sounds. Experiment 1 replicates the well-established finding that listeners categorize more of a [d-g] continuum as [g] after [l] than after [r]. Experiments 2 and 3 show that listeners discriminate stimuli in which the
John, Kingston +5 more
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The Context of Context Effects
Applied Measurement in Education, 1992The principal purpose of this article is to provide a conceptual framework and heuristic model for considering the existence, magnitude, and consequences of context effects. This purpose is addressed through an extension of some concepts in generalizability theory.
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Context-Aware Effective Communications
2021 55th Asilomar Conference on Signals, Systems, and Computers, 2021We investigate the effective communications problem, in which the goal of the transmitter is to impact the actions of the receiver over a time frame in order to maximize the prescribed reward function. This problem is formulated as a multi-agent partially-observable Markov decision process (MA-POMDP), where one agent can communicate to the other ...
Tung T. -Y., Kobus S., Gunduz D.
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Context effects in lexical processing
Cognition, 1987Abstract This article examines the extent to which word recognition is influenced by lexical, syntactic, and semantic contexts in order to contrast predictions made by modular and interactive theories of the architecture of the language comprehension system.
M K, Tanenhaus, M M, Lucas
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