Results 201 to 210 of about 18,917,592 (282)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Context effects on repair of 5'-overhang DNA double-strand breaks induced by Cas12a in Arabidopsis. [PDF]

Plant Direct
Lageix S, Hernandez M, Gallego ME, Verbeke J, Bidet Y, Viala S, White CI.   +6 more
europepmc   +1 more source

Deviations of rational choice: an integrative explanation of the endowment and several context effects. [PDF]

Sci Rep, 2020
Kruis J, Maris G, Marsman M, Bolsinova M, van der Maas HLJ.   +4 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

An investigation into the influence of context effects on crowd exit selection under gender difference in indoor evacuation. [PDF]

Front Psychol
Teng Q, Wang X, He W, Pan G, Mao Y.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Neural and Behavioral Evidence for Frequency-Selective Context Effects in Rhythm Processing in Humans. [PDF]

Cereb Cortex Commun, 2020
Lenc T, Keller PE, Varlet M, Nozaradan S.   +3 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

From Likert to Forced Choice: Statement Parameter Invariance and Context Effects in Personality Assessment. [PDF]

Measurement ( Mahwah N J)
Fu J, Kyllonen PC, Tan X.
europepmc   +1 more source

Where Sounds Occur Matters: Context Effects Influence Processing of Salient Vocalisations. [PDF]

Brain Sci, 2020
Azhari A, Rigo P, Bornstein MH, Esposito G.   +3 more
europepmc   +1 more source