Results 91 to 100 of about 3,574,948 (283)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Ecological Constraints of Timescales, Production, and Perception in Temporal Experiences of Music
Empirical Musicology Review, 2015 In trying to structure our discussions of temporal experience in music, it could be useful to look at some basic ecological constraints of timescales, production, and perception of music.
Rolf Inge Godøy
doaj +1 more source
Career counseling research-practice disparities: What we know and what we need to know
South African Journal of Education, 2017 The most practical principle in contextualisation emanates from our understanding of the experience of everyday life. However, this principle is not confined to such understanding.
Maria Eduarda Duarte
doaj +1 more source
Formalized Mathematics, 2014 Summary Two construction functors: simple term with a variable and compound term with an operation and argument terms and schemes of term induction are introduced. The degree of construction as a number of used operation symbols is defined. Next, the term context is investigated.
openaire +3 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Editorial: Context in Context [PDF]
Foundations of Science, 2002 Edmonds, B., Akman, V.
openaire +2 more sources
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Martingales arising from minimal submanifolds and other geometric contexts [PDF]
, 2015 We consider a class of martingales on Cartan-Hadamard manifolds that includes Brownian motion on a minimal submanifold. We give sufficient conditions for such martingales to be transient, extending previous results on the transience of minimal ...
Neel, Robert W.
core
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source