Results 91 to 100 of about 6,202,666 (342)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Immune class regulation as an integrated response of factors related to host, stimulus and context [PDF]

, 2018
S Prakash
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Developing a coding scheme for analysing classroom dialogue across educational contexts

, 2016
The research reported sought to develop a framework for systematically analysing classroom dialogue for application across a range of educational settings.
S. Hennessy, Sylvia Rojas-Drummond, R. Higham, Ana María Bañuelos Márquez, Fiona Maine, R. M. Ríos, Rocío García-Carrión, Omar Torreblanca, María José Barrera   +8 more
semanticscholar   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

From context to context

Proceedings of the National Academy of Sciences of Belarus, Humanitarian Series, 2019
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openaire   +2 more sources

Using Compass (Context Optimisation Model for Person-Centred Analysis and Systematic Solutions) Theory to Augment Implementation of Digital Health Solutions

, 2022
Carey Mather, Helen Almond
openalex   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Base documentaire sur les artisanats gallo-romains en Lyonnaise et dans les cités du nord et de l’est de l’Aquitaine : Corpus de données. Présentation

Revue Archéologique du Centre de la France, 2009
An important body of all types of craft industries has been built up for the Roman period and is accessible here in context: it concerns the whole of the Lyonnaise Roman province (from Finistère to Lyonnais) as well as the cities of the north and of ...
Alain Ferdière
doaj  

Fathers, Families, and Society: A Two-Decade Systematic Literature Review on the Contexts and Consequences of Paternity and Parental Leave for Fathers

Social Sciences
This systematic literature review assesses two decades of the literature on paternity and parental leave for fathers. We developed a conceptual framework that broadens the understanding of why fathers (do not) use paternity and/or parental leave, and the
Stéfanie André, Nola Cammu, Eline Meuleman   +2 more
doaj   +1 more source