Results 111 to 120 of about 3,574,948 (283)

ConStance: Modeling Annotation Contexts to Improve Stance Classification

open access: yes, 2017
Manual annotations are a prerequisite for many applications of machine learning. However, weaknesses in the annotation process itself are easy to overlook.
Friedland, Lisa   +4 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Ambiguity of Social Networks in Post-Communist Contexts [PDF]

open access: yes, 2004
The paper discusses three hypotheses. First, it introduces four ideal types of networks which are combined in the category of networks as used by social scientists.
Ledeneva, A
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

THE CHANGING FACE OF ORATURE IN POSTCOLONIAL NIGERIA

open access: yesProverbium, 2013
The coming into being of creative writing in English in post-colonial Nigeria since independence and the eminence attained in it as an expressive form by Achebe, Soyinka, Clark, Okigbo and many others, is a cultural revolution.
Nereus Yerima Tadi
doaj  

The evolution of tropos: Contexts, commitments and adaptivity [PDF]

open access: yes, 2010
Software evolution is the main research focus of the Tropos group at University of Trento (UniTN): how do we build systems that are aware of their requirements, and are able to dynamically reconfigure themselves in response to changes in context (the ...
Ali, Raian   +5 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Social prediction errors in assisting strangers: the role of outcomes and contexts

open access: yesFrontiers in Psychology
IntroductionHelping behavior is a fundamental aspect of social interaction, yet little is known about how accurately helpers can predict the emotional responses of help-seekers, particularly when interacting with strangers.MethodsThis study investigated ...
Yan Li, Zhiwei Liu
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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